Medical Surgical Nursing, Manipal College of Nursing, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Radiotherapy & Oncology, KS Hegde Medical Academy, Nitte (Deemed to Be University), Mangalore, Karnataka, India.
Support Care Cancer. 2024 Mar 7;32(4):216. doi: 10.1007/s00520-024-08381-x.
The study aimed at evaluating the Effectiveness of Comprehensive Intervention Programme (CIP) on Quality of life (QOL), fatigue, self-efficacy, and psychosocial distress among Head and Neck Cancer (HNC) patients receiving radiotherapy treatment.
Single-centre non-RCT time series study was conducted among 134 HNC patients (67 observed, followed by 67 subjected to CIP). FACT- H&N, FACT-F, Cancer Behavior Inventory and psychosocial distress scales were used to assess QOL, fatigue, self-efficacy, and psychosocial distress respectively. CIP was provided to the intervention arm twice a week during the course of radiation therapy along with the standard care; the control arm received only standard care. Data were collected before commencing radiotherapy, and post-test assessments were carried out at the end of radiotherapy treatment, and at 3 and 6 months after completion of radiotherapy.
Repeated measures ANOVA revealed a statistically significant improvement with CIP in QOL (F (1.917) = 454.103, p = 0.001), fatigue (F (2.106) = 183.775, p = 0.001), self-efficacy (F (2.429) = 190.861, p = 0.001), and psychosocial distress (F (2.288) = 290.105, p = 0.001) in the intervention arm.
The CIP implemented to address multitude of issues in HNC patients receiving radiotherapy, proved to be effective in reducing the impact of treatment on QOL, fatigue, self-efficacy and psychosocial distress in HNC patients receiving radiotherapy.
本研究旨在评估综合干预方案(CIP)对接受放射治疗的头颈部癌症(HNC)患者的生活质量(QOL)、疲劳、自我效能和心理社会困扰的影响。
对 134 名 HNC 患者(67 例观察,67 例接受 CIP)进行单中心非随机对照时间序列研究。采用 FACT-H&N、FACT-F、癌症行为量表和心理社会困扰量表分别评估 QOL、疲劳、自我效能和心理社会困扰。CIP 在放射治疗过程中每周提供两次,并结合标准护理;对照组仅接受标准护理。在开始放射治疗前收集数据,并在放射治疗结束时、放射治疗结束后 3 个月和 6 个月进行测试评估。
重复测量方差分析显示,CIP 组在 QOL(F(1.917)= 454.103,p = 0.001)、疲劳(F(2.106)= 183.775,p = 0.001)、自我效能(F(2.429)= 190.861,p = 0.001)和心理社会困扰(F(2.288)= 290.105,p = 0.001)方面均有显著改善。
针对接受放射治疗的 HNC 患者存在的多种问题实施的 CIP 证明是有效的,可降低放射治疗对 HNC 患者 QOL、疲劳、自我效能和心理社会困扰的影响。