Tran Thanh Tam Toan, Nguyen Do Mai, Dao Anh Quang, Le Van Thuan, Vasseghian Yasser
Institute of Applied Technology, Thu Dau Mot University, Binh Duong Province, 590000, Viet Nam.
Institute of Applied Technology, Thu Dau Mot University, Binh Duong Province, 590000, Viet Nam.
Chemosphere. 2022 Jun;297:134116. doi: 10.1016/j.chemosphere.2022.134116. Epub 2022 Feb 25.
Venlafaxine (denoted as VFX), a member of the most extensively prescribed antidepressants, is used to handle major depressive disorder, panic disorder and anxiety. This medication affects brain chemistry, which could cause an imbalance in depressed people. VFX and its metabolites, on the other hand, are pollutants in the water environment. Through movement and transformation in several procedures like adsorption, photolysis, hydrolysis and biodegradation, they have harmed living creatures, resulting in the enhancement of diverse active chemicals found in the environment. As a result, determining VFX at modest concentrations with excellent sensitivity, specificity and repeatability are critical. To quantify VFX, various analytical methodologies have been developed. Electroanalytical processes, on the other hand, have piqued interest because of their superior benefits over traditional techniques such as speed, sensitivity, directness and affordability. Subsequently, the purpose of this article is to show how to determine VFX electrochemically using a wide range of electrodes, including CPE, GCE, MCE, SPE, PGE and ISE.
文拉法辛（记为VFX）是使用最为广泛的抗抑郁药物之一，用于治疗重度抑郁症、恐慌症和焦虑症。这种药物会影响大脑化学物质，这可能会导致抑郁症患者体内出现失衡。另一方面，VFX及其代谢物是水环境中的污染物。通过吸附、光解、水解和生物降解等多种过程中的迁移和转化，它们对生物造成了危害，导致环境中发现的多种活性化学物质增加。因此，以优异的灵敏度、特异性和可重复性测定中等浓度的VFX至关重要。为了定量测定VFX，已经开发了各种分析方法。另一方面，电分析方法因其相对于传统技术具有速度快、灵敏度高、直接性和成本低等优势而引起了人们的兴趣。随后，本文的目的是展示如何使用包括碳糊电极（CPE）、玻碳电极（GCE）、汞电极（MCE）、固相萃取电极（SPE）、铂电极（PGE）和离子选择性电极（ISE）在内的多种电极通过电化学方法测定VFX。
