Department of Chemistry, Faculty of Science, Shahid Bahonar University of Kerman, Kerman 76175-133, Iran.
Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman 7631818356, Iran.
Molecules. 2023 Feb 24;28(5):2128. doi: 10.3390/molecules28052128.
We constructed two-dimensional NiCo-metal-organic-framework (NiCo-MOF) nanosheets based on a facile protocol and then characterized them using multiple approaches (X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDS), field emission-scanning electron microscopy (FE-SEM), and N adsorption/desorption isotherms techniques). As a sensitive electroactive material, the as-fabricated bimetallic NiCo-MOF nanosheets were employed to modify a screen-printed graphite electrode surface (NiCo-MOF/SPGE) for epinine electro-oxidation. According to the findings, there was a great improvement in the current responses of the epinine because of the appreciable electron transfer reaction and catalytic performance of the as-produced NiCo-MOF nanosheets. Differential pulse voltammetry (DPV), cyclic voltammetry (CV) and chronoamperometry were utilized to analyze the electrochemical activity of the epinine on the NiCo-MOF/SPGE. A linear calibration plot was obtained in the broad concentration range (0.07-335.0 µM) with a high sensitivity (0.1173 µA/µM) and a commendable correlation coefficient (0.9997). The limit of detection (S/N = 3) was estimated at 0.02 µM for the epinine. According to findings from DPV, the electrochemical sensor of the NiCo-MOF/SPGE could co-detect epinine and venlafaxine. The repeatability, reproducibility and stability of the NiCo-metal-organic-framework-nanosheets-modified electrode were investigated, and the relative standard deviations obtained indicated that the NiCo-MOF/SPGE had superior repeatability, reproducibility and stability. The as-constructed sensor was successfully applicable in sensing the study analytes in real specimens.
我们基于一种简便的方案构建了二维镍钴金属有机骨架（NiCo-MOF）纳米片，并通过多种方法（X 射线衍射（XRD）、能谱（EDS）、场发射扫描电子显微镜（FE-SEM）和 N2 吸附/脱附等温线技术）对其进行了表征。作为一种灵敏的电活性材料，所制备的双金属 NiCo-MOF 纳米片被用于修饰丝网印刷石墨电极表面（NiCo-MOF/SPGE）以进行肾上腺素电氧化。根据研究结果，由于所产生的 NiCo-MOF 纳米片具有可观的电子转移反应和催化性能，肾上腺素的电流响应得到了极大改善。差分脉冲伏安法（DPV）、循环伏安法（CV）和计时电流法用于分析肾上腺素在 NiCo-MOF/SPGE 上的电化学活性。在较宽的浓度范围内（0.07-335.0 µM）获得了线性校准曲线，具有较高的灵敏度（0.1173 µA/µM）和良好的相关系数（0.9997）。肾上腺素的检测限（S/N = 3）估计为 0.02 µM。根据 DPV 的研究结果，NiCo-MOF/SPGE 的电化学传感器可以同时检测肾上腺素和文拉法辛。对 NiCo-MOF/SPGE 修饰电极的重复性、重现性和稳定性进行了研究，得到的相对标准偏差表明 NiCo-MOF/SPGE 具有较高的重复性、重现性和稳定性。所构建的传感器成功地适用于检测实际样品中的研究分析物。
