Homsy Y L, Williot P, Danais S
J Urol. 1986 Jul;136(1 Pt 2):339-41. doi: 10.1016/s0022-5347(17)44860-9.
Hydronephrosis secondary to an anomalous ureteropelvic junction was detected antenatally in more than 60 neonatal renal units Those 21 units that exhibited partial obstruction or dilatation without obstruction were selected for this study. They were assessed and followed by serial diuretic isotope renography (99mtechnetium-diethylenetriaminepentaacetic acid augmented with furosemide) and ultrasonography. Excretory urography was used selectively. Of the 17 renal units that could be assessed 88 per cent demonstrated labile ureteropelvic junctions. Indeed, in 3 to 6 months, when the definitive status seemed to be attained, 41 per cent (7 units) had deteriorated, 12 per cent (2 units) remained stable and 47 per cent (8 units) underwent spontaneous improvement. We recommend a 3 to 6-month observation period for patients with hydronephrosis secondary to ureteropelvic junction anomalies when definite obstruction cannot be confirmed by isotope renography.
超过60个新生儿肾单位在产前被检测出继发于输尿管肾盂连接异常的肾积水。本研究选取了其中21个出现部分梗阻或无梗阻性扩张的肾单位。通过连续的利尿同位素肾图（用速尿增强的99m锝-二乙三胺五乙酸）和超声检查对其进行评估和随访。选择性地使用排泄性尿路造影。在可评估的17个肾单位中，88%显示输尿管肾盂连接不稳定。事实上，在3至6个月时，当似乎达到最终状态时，41%（7个单位）病情恶化，12%（2个单位）保持稳定，47%（8个单位）自发改善。对于继发于输尿管肾盂连接异常的肾积水患者，当同位素肾图不能证实存在明确梗阻时，我们建议进行3至6个月的观察期。
