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新生儿及婴儿的轻度肾积水:超声能否预测膀胱输尿管反流的存在。

Mild hydronephrosis in newborns and infants: can ultrasound predict the presence of vesicoureteral reflux.

作者信息

Berrocal Teresa, Pinilla Inmaculada, Gutiérrez Julia, Prieto Consuelo, de Pablo Luis, Del Hoyo María-Luisa

机构信息

Division of Paediatric Radiology, Department of Radiology, Hospital Universitario La Paz, Paseo Castellana, 261, Madrid, 28046, Spain.

出版信息

Pediatr Nephrol. 2007 Jan;22(1):91-6. doi: 10.1007/s00467-006-0285-1. Epub 2006 Sep 12.

Abstract

The objective of our study was to determine the significance of mild hydronephrosis in newborns and infants as an indicator of vesicoureteral reflux (VUR). The voiding cystourethrography (VCUG) of 573 patients aged 0-18 months with mild, sonographically detected hydronephrosis were reviewed for VUR. Patients with secondary reflux or anomalies making an exact reflux grading impossible were excluded. Normal kidneys, contralateral to hydronephrotic ones, were included. Each kidney was considered separately, forming a total of 1,146 renal units. Mild hydronephrosis was defined as an anteroposterior diameter of the renal pelvis of 0.5-1.5 cm without caliectasis. The International Grading System was used to grade VUR. Seven hundred and thirty-six kidneys had mild hydronephrosis. VUR occurred in 189 out of 736 (25.7%) of these kidneys, and in 108 out of 410 (26.3%) non-distended kidneys, contralateral to hydronephrotic ones (p=0.806). No statistical differences in the frequency of VUR and dilatation were found between the subgroups of patients with and without infection, except for a higher grade of reflux in the group with infection. The frequency of VUR in mildly dilated kidneys was not significantly different from that in non-distended ones. There was a poor correlation between VUR and mild hydronephrosis. The latter should not be considered in itself an indication for VCUG in asymptomatic neonates and infants.

摘要

我们研究的目的是确定新生儿和婴儿轻度肾积水作为膀胱输尿管反流(VUR)指标的意义。对573例年龄在0 - 18个月、经超声检查发现有轻度肾积水的患者进行排尿性膀胱尿道造影(VCUG),以评估是否存在VUR。排除有继发性反流或存在异常而无法准确进行反流分级的患者。纳入与肾积水侧相对的正常肾脏。每个肾脏单独考虑,共形成1146个肾单位。轻度肾积水定义为肾盂前后径为0.5 - 1.5 cm且无肾盏扩张。采用国际分级系统对VUR进行分级。736个肾脏有轻度肾积水。其中189个(25.7%)出现VUR,与肾积水侧相对的410个未扩张肾脏中有108个(26.3%)出现VUR(p = 0.806)。在有感染和无感染的患者亚组之间,除了感染组反流分级较高外,VUR频率和扩张情况无统计学差异。轻度扩张肾脏中VUR的频率与未扩张肾脏中的频率无显著差异。VUR与轻度肾积水之间的相关性较差。对于无症状的新生儿和婴儿,不应将轻度肾积水本身视为进行VCUG的指征。

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