Oncology Hospital, General Hospital of Ningxia Medical University, Yinchua, Ningxia, China.
Department of Pharmacology, College of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia, China.
Chin J Physiol. 2022 Jan-Feb;65(1):12-20. doi: 10.4103/cjp.cjp_89_21.
Breast cancer is one of the most common malignant tumors in women worldwide. Surgery, chemotherapy, and targeted drugs are the main methods currently used in clinical treatment of breast cancer. Although they can improve the symptoms of patients, they are also accompanied by a large number of side effects. Because of its multiple targets, traditional Chinese medicine can improve the quality of life of breast cancer patients and reduce the side effects associated with chemotherapy, which plays an important role in the treatment of breast cancer. To a certain extent, traditional Chinese medicine has advantages that modern medicine does not have in the treatment of breast cancer. Alkaloids are active ingredients widely distributed in traditional Chinese medicine, which have a variety of pharmacological effects including anti-inflammatory, analgesic, and antitumor effects. The author reviewed the literature on the treatment of breast cancer with alkaloids extracted from traditional Chinese medicine in recent years, and discussed the unique advantages of alkaloids in the treatment of breast cancer.
乳腺癌是全球女性最常见的恶性肿瘤之一。手术、化疗和靶向药物是目前临床治疗乳腺癌的主要方法。虽然它们可以改善患者的症状,但也伴随着大量的副作用。由于中药具有多靶点作用,能够提高乳腺癌患者的生活质量,减轻化疗相关的副作用,在乳腺癌的治疗中发挥着重要作用。在一定程度上,中药在治疗乳腺癌方面具有现代医学所不具备的优势。生物碱是广泛分布于中药中的活性成分,具有抗炎、镇痛和抗肿瘤等多种药理作用。作者查阅了近年来从中药中提取的生物碱治疗乳腺癌的文献,探讨了生物碱在治疗乳腺癌方面的独特优势。