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戒烟药物疗法的优化使用。

Optimal use of smoking cessation pharmacotherapy.

作者信息

Mendelsohn Colin

机构信息

Double Bay, Sydney.

出版信息

Aust Prescr. 2022 Feb;45(1):10-14. doi: 10.18773/austprescr.2022.001. Epub 2022 Feb 1.

Abstract

The most effective intervention for stopping smoking is a combination of professional counselling and pharmacotherapy. Medicines are recommended for all smokers who are motivated to quit and are nicotine dependent. Combination nicotine replacement therapy with a patch and an oral product is more effective than the patch alone. An adequate dose of nicotine must be used for an adequate duration. Varenicline is the most effective oral drug. It is safe in people with stable mental illness. Vaping nicotine is a second-line treatment which can be considered for smokers who are unable to quit with other methods.

摘要

戒烟最有效的干预措施是专业咨询与药物治疗相结合。对于所有有戒烟意愿且尼古丁依赖的吸烟者,推荐使用药物。尼古丁贴片和口服产品联合使用的尼古丁替代疗法比单独使用贴片更有效。必须使用足够剂量的尼古丁并持续足够长的时间。伐尼克兰是最有效的口服药物。对患有稳定精神疾病的人来说它是安全的。吸电子烟是一种二线治疗方法,对于无法通过其他方法戒烟的吸烟者可以考虑使用。

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本文引用的文献

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Electronic cigarettes for smoking cessation.电子烟戒烟。
Cochrane Database Syst Rev. 2021 Sep 14;9(9):CD010216. doi: 10.1002/14651858.CD010216.pub6.
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Electronic cigarettes for smoking cessation.电子烟戒烟。
Cochrane Database Syst Rev. 2021 Apr 29;4(4):CD010216. doi: 10.1002/14651858.CD010216.pub5.
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A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy.一项电子烟与尼古丁替代疗法的随机试验。
N Engl J Med. 2019 Feb 14;380(7):629-637. doi: 10.1056/NEJMoa1808779. Epub 2019 Jan 30.
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Nicotine receptor partial agonists for smoking cessation.用于戒烟的尼古丁受体部分激动剂。
Cochrane Database Syst Rev. 2016 May 9;2016(5):CD006103. doi: 10.1002/14651858.CD006103.pub7.

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