I类和II类醛缩酶催化磷酸二羟丙酮和D-果糖1,6-二磷酸中C-1位前手性氢原子的质子交换。
The proton exchange of the pro-S hydrogen atom at C-1 in dihydroxyacetone phosphate and D-fructose 1,6-bisphosphate catalysed by class-I and class-II aldolases.
作者信息
Galdes A, Hill H A
出版信息
Biochem J. 1978 Jun 1;171(3):539-42. doi: 10.1042/bj1710539.
Abstract
The efficacy of class-I and class-II aldolases in catalysing the C-1 proton exchange in fructose 1,6-bisphosphate and dihydroxyacetone phosphate was investigated. The rate of this reaction was at least two orders of magnitude slower in class-II than in the class-I aldolases. It is suggested that this difference reflects the formation of different intermediates in the reactions catalysed by the two classes of aldolase.
摘要
研究了I类和II类醛缩酶催化1,6-二磷酸果糖和磷酸二羟丙酮中C-1质子交换的效率。该反应的速率在II类醛缩酶中比在I类醛缩酶中至少慢两个数量级。有人认为，这种差异反映了两类醛缩酶催化的反应中形成了不同的中间体。
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本文引用的文献
1
Role of Aldolase in Photosynthesis. II Demonstration of Aldolase Types in Photosynthetic Organisms.醛缩酶在光合作用中的作用。II. 光合生物中醛缩酶类型的证明。
Plant Physiol. 1968 May;43(5):793-8. doi: 10.1104/pp.43.5.793.
2
Preparation and properties of yeast aldolase.酵母醛缩酶的制备与性质
J Biol Chem. 1961 Dec;236:3177-84.
3
Comparative properties of yeast and muscle aldolase.酵母醛缩酶与肌肉醛缩酶的比较特性
J Biol Chem. 1961 Dec;236:3185-92.
4
MECHANISM OF THE ALDOLASE REACTION.醛缩酶反应的机制
J Biol Chem. 1965 Apr;240:1758-65.
5
EVOLUTION OF ALDOLASE.醛缩酶的进化
Fed Proc. 1964 Nov-Dec;23:1248-57.
6
Mechanism of C-H bond cleavage in aldolase and isomerase reactions.醛缩酶和异构酶反应中碳氢键断裂的机制。
Brookhaven Symp Biol. 1962 Dec;15:293-309.
7
Studies on the mechanism on the aldolase reaction; isotope exchange reactions of muscle and yeast aldolase.醛缩酶反应机制的研究；肌肉和酵母醛缩酶的同位素交换反应。
J Biol Chem. 1958 Mar;231(1):315-29.
8
Fructose diphosphate aldolase from Fusarium oxysporum f. lycopersici. 3. Studies on the mechanism of reaction.尖孢镰刀菌番茄专化型的果糖二磷酸醛缩酶。3. 反应机制研究。
Can J Biochem. 1967 Dec;45(12):1909-17. doi: 10.1139/o67-224.
9
Studies on the substrates of D-fructose 1,6-diphosphate aldolase in solution.
Biochemistry. 1970 Jun 9;9(12):2454-62. doi: 10.1021/bi00814a010.
10
The function of histidine residues in rabbit muscle aldolase.组氨酸残基在兔肌肉醛缩酶中的作用。
Proc Natl Acad Sci U S A. 1967 Jan;57(1):107-13. doi: 10.1073/pnas.57.1.107.
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