在中国患者中，全膝关节置换术初次手术后使用氨甲环酸，闭式吸引引流并不比不引流带来更多临床益处。

Closed suction drainage offers no more clinical benefit than non-drainage after primary total knee arthroplasty with the administration of tranexamic acid in Chinese patients.

作者信息

Yang Dong, Liu Kaiyuan, Fan Lin, Xu Tianyang, Li Guodong

机构信息

Department of Orthopedics, Shanghai Tenth People's Hospital, No. 301, Yanchang Road, Shanghai, 200072, People's Republic of China.

出版信息

Arthroplasty. 2020 Jun 23;2(1):18. doi: 10.1186/s42836-020-00035-7.

BACKGROUND

If closed suction drainage (CSD) should be used after primary total knee arthroplasty (TKA), remains controversial. The current study aimed to explore whether CSD offers more clinical benefit with the administration of tranexamic acid in Chinese patients.

METHODS

A retrospective study was conducted on 200 patients who had received TKA. One hundred patients were placed on drainage after TKA, whereas the rest of 100 patients were not. Multiple clinical parameters were dynamically monitored and compared between the two groups.

RESULTS

The length of the hospitalization days was significantly shorter in patients who did not receive CSD (6.0 ± 0.8 vs. 7.0 ± 0.8 days, p < 0.001). The patients in the drainage group had more Hb drop on the first postoperative day (14.82 ± 6.58 vs. 11.27 ± 5.71 g/L, p < 0.001). No statistically significant difference was observed in VAS score, ROM and thigh circumference at baseline during the follow-up between two groups.

CONCLUSIONS

Additional drainage after primary TKA had no clinical benefit after the tranexamic acid had already been administered during the treatment.

背景

初次全膝关节置换术（TKA）后是否应使用闭式吸引引流（CSD）仍存在争议。本研究旨在探讨在中国患者中，CSD联合氨甲环酸给药是否能带来更多临床益处。

方法

对200例行TKA的患者进行回顾性研究。100例患者在TKA后进行引流，其余100例患者未进行引流。对两组患者的多项临床参数进行动态监测和比较。

结果

未接受CSD的患者住院天数显著缩短（6.0±0.8天 vs. 7.0±0.8天，p<0.001）。引流组患者术后第一天血红蛋白下降更多（14.82±6.58 vs. 11.27±5.71 g/L，p<0.001）。两组随访期间基线时的视觉模拟评分（VAS）、关节活动度（ROM）和大腿围度无统计学显著差异。