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白细胞酯酶试纸条检测在人工关节周围感染筛查中的应用及高精度试纸条的前景

Application of leukocyte esterase strip test in the screening of periprosthetic joint infections and prospects of high-precision strips.

作者信息

Zheng Qing-Yuan, Zhang Guo-Qiang

机构信息

Department of Orthopedics, the Fourth Medical Center, Chinese PLA General Hospital, 51 Fucheng Road, Beijing, IL 60016, China.

出版信息

Arthroplasty. 2020 Oct 29;2(1):34. doi: 10.1186/s42836-020-00053-5.

DOI:10.1186/s42836-020-00053-5
PMID:35236471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8796411/
Abstract

Periprosthetic joint infection (PJI) represents one of the most challenging complications after total joint arthroplasty (TJA). Despite the availability of a variety of diagnostic techniques, the diagnosis of PJI remains a challenge due to the lack of well-established diagnostic criteria. The leucocyte esterase (LE) strips test has been proved to be a valuable diagnostic tool for PJI, and its weight in PJI diagnostic criteria has gradually increased. Characterized by its convenience, speed and immediacy, leucocyte esterase strips test has a prospect of broad application in PJI diagnosis. Admittedly, the leucocyte esterase strips test has some limitations, such as imprecision and liability to interference. Thanks to the application of new technologies, such as machine reading, quantitative detection and artificial intelligence, the LE strips test is expected to overcome the limitations and improve its accuracy.

摘要

人工关节周围感染(PJI)是全关节置换术(TJA)后最具挑战性的并发症之一。尽管有多种诊断技术可用,但由于缺乏成熟的诊断标准,PJI的诊断仍然是一项挑战。白细胞酯酶(LE)试纸条检测已被证明是一种用于PJI的有价值的诊断工具,其在PJI诊断标准中的权重逐渐增加。白细胞酯酶试纸条检测具有方便、快速和即时的特点,在PJI诊断中具有广泛应用的前景。诚然,白细胞酯酶试纸条检测存在一些局限性,如不精确和易受干扰。得益于机器读取、定量检测和人工智能等新技术的应用,LE试纸条检测有望克服这些局限性并提高其准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f6/8796411/72f03290ff18/42836_2020_53_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f6/8796411/72f03290ff18/42836_2020_53_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f6/8796411/72f03290ff18/42836_2020_53_Fig1_HTML.jpg

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Infection Screening in Biofluids with Glucose Test Strips.生物流体中的葡萄糖测试条感染筛查。
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