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亚洲旅行者腹泻的病因与流行病学

Etiology and epidemiology of travelers' diarrhea in Asia.

作者信息

Taylor D N, Echeverria P

出版信息

Rev Infect Dis. 1986 May-Jun;8 Suppl 2:S136-41. doi: 10.1093/clinids/8.supplement_2.s136.

DOI:10.1093/clinids/8.supplement_2.s136
PMID:3523709
Abstract

Travelers' diarrhea in Asia has been studied among Peace Corps volunteers in Thailand, Japanese travelers, foreign residents in Bangladesh, guests in hotels, and members of various tour groups. Rates of diarrheal attack of greater than 50% during four- to six-week sojourns were reported for these groups. Among travelers with diarrhea, the most commonly isolated pathogen was enterotoxigenic Escherichia coli (20%-34%), followed by Salmonella (11%-15%), Shigella (4%-7%), Campylobacter (2%-5%), and Vibrio parahaemolyticus (1%-13%). In 9%-22% of diarrheal episodes, multiple pathogens were recovered. Among Japanese travelers, Salmonella was more commonly acquired in the Far East; Shigella and Campylobacter, in the Indian subcontinent; and V. parahaemolyticus, in Southeast Asia. Aeromonas hydrophila and Plesiomonas shigelloides were commonly isolated from ill travelers in Thailand but less frequently from other travelers. Protozoa and Vibrio species other than V. parahaemolyticus were isolated in less than 5% of episodes.

摘要

在泰国的和平队志愿者、日本旅行者、孟加拉国的外国居民、酒店客人以及各类旅游团成员中,对亚洲旅行者腹泻情况进行了研究。据报告,这些群体在四至六周的逗留期间腹泻发病率超过50%。在腹泻的旅行者中,最常分离出的病原体是产肠毒素大肠杆菌(20%-34%),其次是沙门氏菌(11%-15%)、志贺氏菌(4%-7%)、弯曲杆菌(2%-5%)和副溶血性弧菌(1%-13%)。在9%-22%的腹泻病例中,分离出多种病原体。在日本旅行者中,沙门氏菌在远东地区更为常见;志贺氏菌和弯曲杆菌在印度次大陆更为常见;副溶血性弧菌在东南亚更为常见。嗜水气单胞菌和类志贺邻单胞菌在泰国患病旅行者中常被分离出,但在其他旅行者中较少见。除副溶血性弧菌外的原生动物和弧菌属在不到5%的病例中被分离出。

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