Zunyi Medical University, Zunyi, Guizhou, China.
Department of Cardio-Thoracic Surgery, Chengdu Second People's Hospital, Chengdu, Sichuan, China.
Heart Surg Forum. 2022 Feb 16;25(1):E118-E123. doi: 10.1532/hsf.4395.
Postoperative cognitive dysfunction (POCD) refers to a complication of neurological dysfunction after surgery, including one or more changes that are significantly lower than those before surgery. The purpose of this study was to review the coping strategies and risk factors of POCD.A systemic research was conducted searching Pubmed, web of science, MEDLINE and other websites with the keywords of cardiac surgery, cognitive impairment and POCD. Multiple factors have been associated with the treatment of POCD, including anesthetic, choice of analgesic drugs, anti-inflammatory drugs, erythropoietin, atherosclerosis, emotional factors, surgical and other factors. Targeted treatments are carried out for risk factors that may affect POCD prevention, such as anesthetic drug prevention, anti-inflammatory drug prevention, and intraoperative prevention and other preventive measures are aimed at reducing the incidence of POCD after cardiac surgery.
术后认知功能障碍（POCD）是指手术后神经功能障碍的一种并发症，包括一种或多种显著低于术前的变化。本研究旨在回顾 POCD 的应对策略和危险因素。通过关键词“心脏手术、认知障碍和 POCD”在 Pubmed、web of science、MEDLINE 和其他网站上进行系统研究。多种因素与 POCD 的治疗有关，包括麻醉、镇痛药物选择、抗炎药物、促红细胞生成素、动脉粥样硬化、情绪因素、手术和其他因素。针对可能影响 POCD 预防的危险因素进行有针对性的治疗，如预防麻醉药物、预防抗炎药物以及术中预防等预防措施，旨在降低心脏手术后 POCD 的发生率。
