College of Chemistry and Chemical Engineering, Hubei University, 430062 Wuhan, People's Republic of China.
School of Mechanical Science and Engineering, Huazhong University of Science and Technology, 430074 Wuhan, People's Republic of China.
Anal Chem. 2022 Mar 15;94(10):4547-4555. doi: 10.1021/acs.analchem.2c00593. Epub 2022 Mar 3.
Wearable sweat sensing is essential to the development of personalized health monitoring in a noninvasive manner with molecular-level insight. Hence, there is an increasing demand for convenient, facile, and efficient fabrication of wearable sensing arrays. Inspired by a photosensitive stamp (PS), we present herein a simple, low-cost, and eco-friendly vacuum filtration-transfer printing method (termed PS-VFTP) for the scalable preparation of single-walled carbon nanotube (SWCNT) based flexible electrode arrays. This method can economically yield customized flexible SWCNT arrays with praiseworthy performance, such as high reproducibility, precision, uniformity, conductivity, and mechanical stability. In addition, the flexible SWCNT arrays can be easily functionalized into high-performance electrochemical sensors for the simultaneous monitoring of sweat metabolites (glucose, lactate) and electrolytes (Na, K). The integration of wearable sensing arrays with a signal acquisition and processing circuit system in the intelligent wearable sensors empowers them to realize noninvasive, real-time, and sweat analysis during exercise. More meaningfully, such a PS-VFTP strategy can be easily expanded to the economical manufacturing of other flexible electronic devices.
可穿戴汗液传感对于以非侵入方式实现分子水平的个性化健康监测至关重要。因此，人们对方便、简单和高效的可穿戴传感阵列制造方法的需求日益增加。受光敏印章（PS）的启发，我们在此提出了一种简单、低成本且环保的真空过滤-转移打印方法（称为 PS-VFTP），用于可扩展地制备基于单壁碳纳米管（SWCNT）的柔性电极阵列。这种方法可以经济地获得具有出色性能的定制化柔性 SWCNT 阵列，例如高重复性、精度、均匀性、导电性和机械稳定性。此外，柔性 SWCNT 阵列可以轻松功能化为高性能电化学传感器，用于同时监测汗液代谢物（葡萄糖、乳酸）和电解质（Na、K）。将可穿戴传感阵列与智能可穿戴传感器中的信号采集和处理电路系统集成，使其能够在运动过程中实现非侵入式、实时和汗液分析。更有意义的是，这种 PS-VFTP 策略可以很容易地扩展到其他柔性电子设备的经济制造。
