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GLP-1 (Glucagon-Like Peptide-1) Plays a Role in Carotid Chemoreceptor-Mediated Sympathoexcitation and Hypertension.

作者信息

Zucker Irving H, Wang Han-Jun, Schultz Harold D

机构信息

Department of Cellular and Integrative Physiology (I.H.Z., H.D.S.), University of Nebraska Medical Center.

Department of Anesthesiology (H.W.), University of Nebraska Medical Center.

出版信息

Circ Res. 2022 Mar 4;130(5):708-710. doi: 10.1161/CIRCRESAHA.122.320799. Epub 2022 Mar 3.

DOI:10.1161/CIRCRESAHA.122.320799
PMID:35239402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8909667/
Abstract
摘要

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本文引用的文献

1
GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition.GLP1R 通过颈动脉体抑制来减轻高血糖引起的交感神经反应。
Circ Res. 2022 Mar 4;130(5):694-707. doi: 10.1161/CIRCRESAHA.121.319874. Epub 2022 Feb 1.
2
Carotid body chemoreceptors: physiology, pathology, and implications for health and disease.颈动脉体化学感受器:生理学、病理学及对健康和疾病的影响。
Physiol Rev. 2021 Jul 1;101(3):1177-1235. doi: 10.1152/physrev.00039.2019. Epub 2021 Feb 11.
3
Functional interaction between Ghrelin and GLP-1 regulates feeding through the vagal afferent system.
Ghrelin 和 GLP-1 之间的功能相互作用通过迷走传入系统调节进食。
Sci Rep. 2020 Oct 28;10(1):18415. doi: 10.1038/s41598-020-75621-5.
4
Central Glucagon-like Peptide-1 Receptor Signaling via Brainstem Catecholamine Neurons Counteracts Hypertension in Spontaneously Hypertensive Rats.通过脑干儿茶酚胺神经元的中央胰高血糖素样肽-1 受体信号传导可抵抗自发性高血压大鼠的高血压。
Sci Rep. 2019 Sep 19;9(1):12986. doi: 10.1038/s41598-019-49364-x.
5
Glucagon-like peptide 1 receptor (GLP-1R) expression by nerve fibres in inflammatory bowel disease and functional effects in cultured neurons.神经纤维中胰高血糖素样肽 1 受体 (GLP-1R) 在炎症性肠病中的表达及其对培养神经元的功能影响。
PLoS One. 2018 May 29;13(5):e0198024. doi: 10.1371/journal.pone.0198024. eCollection 2018.
6
KLF2 mediates enhanced chemoreflex sensitivity, disordered breathing and autonomic dysregulation in heart failure.KLF2 介导心力衰竭时化学感受反射敏感性增强、呼吸紊乱和自主神经调节障碍。
J Physiol. 2018 Aug;596(15):3171-3185. doi: 10.1113/JP273805. Epub 2017 Oct 11.
7
The structural factor of hypertension: large and small artery alterations.高血压的结构因素:大动脉和小动脉的改变。
Circ Res. 2015 Mar 13;116(6):1007-21. doi: 10.1161/CIRCRESAHA.116.303596.
8
Mechanisms of carotid body chemoreflex dysfunction during heart failure.心力衰竭期间颈动脉体化学反射功能障碍的机制。
Exp Physiol. 2015 Feb 1;100(2):124-9. doi: 10.1113/expphysiol.2014.079517. Epub 2015 Jan 15.
9
Glucose sensing by carotid body glomus cells: potential implications in disease.颈动脉体小球细胞的葡萄糖感应:疾病中的潜在意义。
Front Physiol. 2014 Oct 15;5:398. doi: 10.3389/fphys.2014.00398. eCollection 2014.
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The autonomic nervous system and hypertension.自主神经系统与高血压。
Circ Res. 2014 May 23;114(11):1804-14. doi: 10.1161/CIRCRESAHA.114.302524.