Luminal Oxidative Regulation of the Ryanodine Receptor: More Sides to the Story?
作者信息
van Opbergen Chantal J M, Pérez-Hernández Marta, Delmar Mario
机构信息
Leon H Charney Division of Cardiology, Department of Medicine, NYU-Grossman School of Medicine, NY (C.J.M.v.O., M.P.-H., M.D.).
出版信息
Circ Res. 2022 Mar 4;130(5):725-727. doi: 10.1161/CIRCRESAHA.122.320798. Epub 2022 Mar 3.
Abstract
摘要
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Luminal Oxidative Regulation of the Ryanodine Receptor: More Sides to the Story?兰尼碱受体的管腔氧化调节：故事还有更多面？
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本文引用的文献
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Ero1α-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia.Ero1α 依赖性 ERp44 从 RyR2 上解离导致心律失常。
Circ Res. 2022 Mar 4;130(5):711-724. doi: 10.1161/CIRCRESAHA.121.320531. Epub 2022 Jan 28.
2
Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: a translational study.桥粒斑蛋白-2 表达在运动相关致心律失常性右室心肌病进展中的作用：一项转化研究。
Eur Heart J. 2022 Mar 21;43(12):1251-1264. doi: 10.1093/eurheartj/ehab772.
3
Mechanisms of ryanodine receptor 2 dysfunction in heart failure.心力衰竭中兰尼碱受体2功能障碍的机制。
Nat Rev Cardiol. 2020 Nov;17(11):748. doi: 10.1038/s41569-020-00443-x.
4
Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS.钙漏诱导的线粒体 ROS 加剧了 RyR2 活性的增加。
Basic Res Cardiol. 2020 May 22;115(4):38. doi: 10.1007/s00395-020-0797-z.
5
Disruption of Ca Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice.钙稳态破坏和缝隙连接蛋白 43 半通道功能障碍先于桥粒斑蛋白-2 缺陷小鼠出现显性致心律失常性心肌病。
Circulation. 2019 Sep 17;140(12):1015-1030. doi: 10.1161/CIRCULATIONAHA.119.039710. Epub 2019 Jul 18.
6
Accentuated vagal antagonism paradoxically increases ryanodine receptor calcium leak in long-term exercised Calsequestrin2 knockout mice.增强的迷走神经拮抗作用反使长期运动的 Calsequestrin2 敲除小鼠的兰尼碱受体钙漏增加。
Heart Rhythm. 2018 Mar;15(3):430-441. doi: 10.1016/j.hrthm.2017.10.008. Epub 2017 Oct 10.
7
Posttranslational modifications of cardiac ryanodine receptors: Ca(2+) signaling and EC-coupling.心脏兰尼碱受体的翻译后修饰：Ca(2+)信号传导与兴奋-收缩偶联
Biochim Biophys Acta. 2013 Apr;1833(4):866-75. doi: 10.1016/j.bbamcr.2012.08.016. Epub 2012 Aug 31.
8
Oxidative stress in heart failure: what are we missing?心力衰竭中的氧化应激：我们遗漏了什么？
Am J Med Sci. 2011 Aug;342(2):120-4. doi: 10.1097/MAJ.0b013e3182249fcd.
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Inherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis.肌浆网 Ca2+ 处理功能遗传性缺陷与心律失常发生。
Circ Res. 2011 Apr 1;108(7):871-83. doi: 10.1161/CIRCRESAHA.110.226845.
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Scavenging free radicals by low-dose carvedilol prevents redox-dependent Ca2+ leak via stabilization of ryanodine receptor in heart failure.低剂量卡维地洛清除自由基可通过稳定心力衰竭时的兰尼碱受体来防止氧化还原依赖性Ca2+泄漏。
J Am Coll Cardiol. 2007 Apr 24;49(16):1722-32. doi: 10.1016/j.jacc.2007.01.064. Epub 2007 Apr 5.
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