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田纳西州 HIV 感染者与 HIV 护理衔接相关的个体、社区和结构因素。

Individual, community, and structural factors associated with linkage to HIV care among people diagnosed with HIV in Tennessee.

机构信息

Department of Medicine, Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, United States of America.

Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN, United States of America.

出版信息

PLoS One. 2022 Mar 3;17(3):e0264508. doi: 10.1371/journal.pone.0264508. eCollection 2022.

Abstract

OBJECTIVE

We assessed trends and identified individual- and county-level factors associated with individual linkage to HIV care in Tennessee (TN).

METHODS

TN residents diagnosed with HIV from 2012-2016 were included in the analysis (n = 3,751). Individuals were assigned county-level factors based on county of residence at the time of diagnosis. Linkage was defined by the first CD4 or HIV RNA test date after HIV diagnosis. We used modified Poisson regression to estimate probability of 30-day linkage to care at the individual-level and the contribution of individual and county-level factors to this outcome.

RESULTS

Both MSM (aRR 1.23, 95%CI 0.98-1.55) and women who reported heterosexual sex risk factors (aRR 1.39, 95%CI 1.18-1.65) were more likely to link to care within 30-days than heterosexual males. Non-Hispanic Black individuals had poorer linkage than White individuals (aRR 0.77, 95%CI 0.71-0.83). County-level mentally unhealthy days were negatively associated with linkage (aRR 0.63, 95%CI: 0.40-0.99).

CONCLUSIONS

Racial disparities in linkage to care persist at both individual and county levels, even when adjusting for county-level social determinants of health. These findings suggest a need for structural interventions to address both structural racism and mental health needs to improve linkage to care and minimize racial disparities in HIV outcomes.

摘要

目的

我们评估了田纳西州(TN)与个体获得 HIV 护理机会相关的趋势和个体及县一级因素。

方法

本分析纳入了 2012 年至 2016 年期间在 TN 被诊断为 HIV 的居民(n=3751)。根据诊断时的居住县,将个体分配到县一级因素中。将 HIV 诊断后首次 CD4 或 HIV RNA 检测日期定义为关联。我们使用修正泊松回归来估计个体水平 30 天内获得护理的关联概率以及个体和县级因素对这一结果的贡献。

结果

男男性行为者(MSM)(ARR 1.23,95%CI 0.98-1.55)和报告异性性传播风险因素的女性(ARR 1.39,95%CI 1.18-1.65)比异性男性更有可能在 30 天内获得护理。非西班牙裔黑人比白人更不容易获得护理(ARR 0.77,95%CI 0.71-0.83)。县一级心理健康不良天数与关联呈负相关(ARR 0.63,95%CI:0.40-0.99)。

结论

即使在调整了县级健康的社会决定因素后,个体和县级层面的护理关联仍然存在种族差异。这些发现表明,需要采取结构性干预措施,解决结构性种族主义和心理健康需求,以改善护理关联,并最大限度地减少 HIV 结果中的种族差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c704/8893655/bdcc1356eb44/pone.0264508.g001.jpg

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