Bottoms S F, Welch R A, Zador I E, Sokol R J
Am J Obstet Gynecol. 1986 Jul;155(1):154-8. doi: 10.1016/0002-9378(86)90101-8.
Maximum vertical pocket measurement and subjective sonographic impression of amniotic fluid volume were studied in 487 selected pregnancies. Opiate abuse, suspected fetal growth retardation, and suspected postterm gestation were negatively correlated with maximum vertical pocket; suspected fetal growth acceleration and increasing birth weight were positively correlated. Maximum vertical pocket appeared to peak at 31 to 33 weeks (p less than 0.05), and was related to fetal growth (p less than 0.001). Subjective sonographic evaluation of amniotic fluid volume yielded comparable results. Unfortunately, neither technique could be used to accurately predict the birth of a small, appropriate, or large for gestational age infant in the individual pregnancy. Abnormal fetal growth could be reliably excluded in only a small number of cases. This and previous studies suggest that diagnosis of abnormal fetal growth by means of sonographic amniotic fluid volume evaluation could be limited by physiologic variation rather than technical error in measurement.
在487例选定的妊娠中，研究了羊水最大垂直深度测量值和羊水容量的主观超声印象。阿片类药物滥用、疑似胎儿生长受限和疑似过期妊娠与羊水最大垂直深度呈负相关；疑似胎儿生长加速和出生体重增加呈正相关。羊水最大垂直深度似乎在孕31至33周时达到峰值（p<0.05），且与胎儿生长有关（p<0.001）。羊水容量的主观超声评估也得出了类似结果。遗憾的是，这两种技术均无法准确预测个体妊娠中小于胎龄儿、适于胎龄儿或大于胎龄儿的出生情况。仅在少数病例中能可靠地排除胎儿生长异常。本研究及先前的研究表明，通过超声评估羊水量来诊断胎儿生长异常可能受生理变异限制，而非测量技术误差所致。
