Tsampasian Vasiliki, Hothi Sandeep S, Ravindrarajah Thuwarahan, Swift Andrew J, Garg Pankaj, Vassiliou Vassilios S
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
Norfolk and Norwich University Hospital, Norwich, UK.
Cardiol Res Pract. 2022 Feb 22;2022:3144386. doi: 10.1155/2022/3144386. eCollection 2022.
Cardiovascular magnetic resonance (CMR) imaging has had a vast impact on the understanding of a wide range of disease processes and pathophysiological mechanisms. More recently, it has contributed significantly to the diagnosis and risk stratification of patients with valvular heart disease. With its increasing use, CMR allows for a detailed, reproducible, qualitative, and quantitative evaluation of left ventricular volumes and mass, thereby enabling assessment of the haemodynamic impact of a valvular lesion upon the myocardium. Postprocessing of the routinely acquired images with feature tracking CMR methodology can give invaluable information about myocardial deformation and strain parameters that suggest subclinical ventricular impairment that remains undetected by conventional measures such as the ejection fraction (EF). T1 mapping and late gadolinium enhancement (LGE) imaging provide deep myocardial tissue characterisation that is changing the approach towards risk stratification of patients as an increasing body of evidence suggests that the presence of fibrosis is related to adverse events and prognosis. This review summarises the current evidence regarding the utility of CMR in the left ventricular assessment of patients with aortic stenosis or mitral regurgitation and its value in diagnosis, risk stratification, and management.
心血管磁共振(CMR)成像对理解广泛的疾病过程和病理生理机制产生了巨大影响。最近,它对心脏瓣膜病患者的诊断和风险分层做出了重大贡献。随着其使用的增加,CMR能够对左心室容积和质量进行详细、可重复、定性和定量评估,从而能够评估瓣膜病变对心肌的血流动力学影响。使用特征跟踪CMR方法对常规采集的图像进行后处理,可以提供有关心肌变形和应变参数的宝贵信息,这些参数提示存在传统测量方法(如射血分数(EF))未检测到的亚临床心室功能损害。T1映射和延迟钆增强(LGE)成像提供了深入的心肌组织特征描述,随着越来越多的证据表明纤维化的存在与不良事件和预后相关,这正在改变对患者进行风险分层的方法。本综述总结了关于CMR在主动脉瓣狭窄或二尖瓣反流患者左心室评估中的效用及其在诊断、风险分层和管理中的价值的当前证据。