Motoo Yoshiharu, Cameron Silke
Department of Medical Oncology and Kampo Medicine, Komatsu Sophia Hospital, Komatsu, Ishikawa, Japan.
Clinic for Gastroenterology and Gastrointestinal Oncology, University of Göttingen Medical School, Göttingen, Germany.
Integr Med Res. 2022 Jun;11(2):100839. doi: 10.1016/j.imr.2022.100839. Epub 2022 Feb 23.
Kampo medicines, which are standardized traditional Japanese herbal medicines, have been tried to support patients with cancer.
Randomized controlled trials on the use of Kampo medicines for cancer supportive care and the descriptions of Kampo medicines in clinical practice guidelines were reviewed.
Kampo medicines potentially ameliorate refractory symptoms in cancer patients. For example, hochuekkito, juzentaihoto, and ninjin'yoeito seem to be efficacious for fatigue/general malaise. Potential use of rikkunshito for anorexia/cancer cachexia and goshajinkigan for peripheral neuropathy is proposed from small numbers of randomized controlled trials in addition to basic research. The number of clinical practice guidelines which contain descriptions of Kampo medicines is increasing in general, but only a few in the area of cancer supportive care.
Kampo medicines potentially play some roles in preventing or ameliorating side effects of anticancer agents. Supportive care with Kampo medicines for patients with cancer might lead to physical, mental, and nutritional improvement.
汉方药物是标准化的传统日本草药，已尝试用于支持癌症患者。
回顾了关于使用汉方药物进行癌症支持治疗的随机对照试验以及临床实践指南中对汉方药物的描述。
汉方药物可能改善癌症患者的难治性症状。例如，补中益气汤、十全大补汤和人参养荣汤似乎对疲劳/全身不适有效。除基础研究外，少量随机对照试验提出了理气剂用于厌食/癌症恶病质以及五倍子汤用于周围神经病变的潜在用途。总体而言，包含汉方药物描述的临床实践指南数量在增加，但在癌症支持治疗领域仅有少数。
汉方药物可能在预防或改善抗癌药物的副作用方面发挥一些作用。对癌症患者使用汉方药物进行支持治疗可能会改善身体、心理和营养状况。
