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单绒毛膜双羊膜囊双胎中以母体低钠血症为表现的镜像综合征:一例报告

Mirror syndrome in monochorionic diamniotic twins presenting as maternal hyponatremia: A case report.

作者信息

Hussain Farrah Naz, Parikh Bijal, Shenoy Mangalore S, Al-Ibraheemi Zainab, Lewis Dawnette

机构信息

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Mount Sinai West, Icahn School of Medicine at Mount Sinai, 1000 10 Ave, New York, NY 10019, United States of America.

Division of Nephrology, Department of Medicine, Mount Sinai West, Icahn School of Medicine at Mount Sinai, 1000 10 Ave, New York, NY 10019, United States of America.

出版信息

Case Rep Womens Health. 2022 Feb 17;34:e00401. doi: 10.1016/j.crwh.2022.e00401. eCollection 2022 Apr.

Abstract

This is a case report of a 39-year-old patient, G5P1031, with monochorionic diamniotic twins at 30 weeks and 1 day of gestation, who developed mirror syndrome without twin-to-twin transfusion syndrome (TTTS) with a unique presentation of maternal and neonatal hyponatremia. Coinciding with severe hyponatremia were maternal symptoms of edema, nausea and vomiting, hypoalbuminemia, elevated uric acid, as well as fetal selective growth restriction, polyhydramnios, umbilical artery absent end diastolic flow and prolonged bradycardia of twin B. Given the poor status of twin B and the risks to twin A, the patient underwent emergent cesarean delivery. Hyponatremia in all three patients resolved in the following 48-72 h. Mirror syndrome is associated with significant maternal and fetal morbidity and mortality. In this case, severe hyponatremia posed additional risks. Therefore, electrolyte monitoring should be considered in both mother and neonate(s).

摘要

这是一例39岁患者的病例报告,患者孕次5产次1(G5P1031),妊娠30周零1天,为单绒毛膜双羊膜囊双胎,未发生双胎输血综合征(TTTS)却出现了镜像综合征,伴有母体和新生儿低钠血症这一独特表现。与严重低钠血症同时出现的母体症状有水肿、恶心和呕吐、低白蛋白血症、尿酸升高,以及胎儿选择性生长受限、羊水过多、脐动脉舒张末期血流消失和双胎B心动过缓延长。鉴于双胎B状况不佳以及对双胎A存在风险,患者接受了紧急剖宫产。所有三名患者的低钠血症在接下来的48 - 72小时内得到缓解。镜像综合征与显著的母体和胎儿发病及死亡相关。在本病例中,严重低钠血症带来了额外风险。因此,应考虑对母亲和新生儿进行电解质监测。

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