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[呼气末正压对肺泡蛋白沉积症患者支气管肺泡灌洗术中动脉氧合的影响]

[Effect of positive end expiratory pressure on arterial oxygenation during bronchoalveolar lavage for proteinosis].

作者信息

Julien T, Caudine M, Barlet H, Wintrebert P, Aubas P, du Cailar J

出版信息

Ann Fr Anesth Reanim. 1986;5(2):173-6. doi: 10.1016/s0750-7658(86)80104-6.

Abstract

To maintain good cellular oxygenation during bronchopulmonary lavage for alveolar proteinosis is often a difficult problem to solve. A case is reported of alveolar proteinosis in whom four lavages were performed. Details of the technique are discussed, as are the problems with expedients used to improve PaO2. The use of a 10 cmH2O positive end-expiratory pressure was useful only during the "in-phase"; in the "out-phase", it worsened the PaO2. PaO2 during lavage in patients with alveolar proteinosis can only be improved by three ways: cancellation of the shunt during lung filling and, during the "out-phase", an increase in FIO2 or pulmonary artery occlusion by a balloon.

摘要

在肺泡蛋白沉积症的支气管肺灌洗过程中,维持良好的细胞氧合常常是一个难以解决的问题。本文报告了一例进行了四次灌洗的肺泡蛋白沉积症病例。文中讨论了该技术的细节以及用于改善动脉血氧分压(PaO2)的应急措施所存在的问题。使用10厘米水柱的呼气末正压仅在“进气期”有用;在“出气期”,它会使PaO2恶化。肺泡蛋白沉积症患者灌洗期间的PaO2只能通过三种方法改善:在肺充盈时消除分流,以及在“出气期”增加吸入氧分数(FIO2)或用球囊阻断肺动脉。

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