Akhtar Naveed, Abid Fatma, Singh Rajvir, Kamran Saadat, Imam Yahia, Al Jerdi Salman, Salameh Sarah, Al Attar Rand, Yasir Muhammad, Shabir Hammad, Morgan Deborah, Joseph Sujatha, AlMaslamani Muna, Shuaib Ashfaq
The Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar.
Infectious Diseases Section, Medicine Department, Hamad Medical Corporation, Doha, Qatar.
J Thromb Thrombolysis. 2022 May;53(4):824-828. doi: 10.1007/s11239-021-02581-6. Epub 2022 Mar 4.
Understanding the relationship of COVID-19 to stroke is important. We compare characteristics of pre-pandemic stroke (PPS), cases in acute COVID infection (CS) and in patients who have recovered from COVID-19 infection (RCS). We interrogated the Qatar stroke database for all stroke admissions between Jan 2020 and Feb 2021 (PPS) to CS and RCS to determine how COVID-19 affected ischemic stroke sub-types, clinical course, and outcomes prior to, during and post-pandemic peak. There were 3264 cases admitted (pre-pandemic: 3111, stroke in COVID-19: 60 and recovered COVID-19 stroke: 93). Patients with CS were significantly younger, had more severe symptoms, fever on presentation, more ICU admissions and poor stroke recovery at discharge when compared to PPS and RCS. Large vessel disease and cardioembolic disease was significantly higher in CS compared to PPS or RCS. There was a significant decline in stroke mimics in CS. Stroke in RCS has characteristics similar to PPS with no evidence of lasting effects of the virus on the short-term. However, CS is a more serious disease and tends to be more severe and have a poor prognosis.
了解新型冠状病毒肺炎（COVID-19）与中风之间的关系很重要。我们比较了疫情前中风（PPS）、急性COVID感染病例（CS）以及COVID-19感染康复患者（RCS）的特征。我们查询了卡塔尔中风数据库中2020年1月至2021年2月期间所有中风入院病例（PPS），以及CS和RCS病例，以确定COVID-19如何影响缺血性中风亚型、临床病程以及疫情高峰前、期间和之后的预后。共收治3264例病例（疫情前：3111例，COVID-19中风：60例，COVID-19康复后中风：93例）。与PPS和RCS相比，CS患者明显更年轻，症状更严重，就诊时发热，入住重症监护病房的比例更高，出院时中风恢复情况较差。与PPS或RCS相比，CS患者的大血管疾病和心源性栓塞疾病显著更多。CS患者中类似中风的疾病显著减少。RCS患者的中风特征与PPS相似，没有证据表明病毒对短期有持久影响。然而，CS是一种更严重的疾病，往往更严重，预后较差。
