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亚甲蓝试验,一项有风险的介入:病例报告。

The methylene blue test, a risky intervention: A case report.

出版信息

Tunis Med. 2021;99(5):582-584.

PMID:35244909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8772596/
Abstract

Methylene blue is used to check tubal patency during laparoscopy. We report the case of a 28-year-old patient who presented a blue coloring of the skin, mucous membranes and nails after methylene blue test during laparoscopy for infertility.  The oxygen saturation was 82%. The patient was hospitalized for 48 hours in the intensive care unit and spectrophotometric analysis revealed a methemoglobin level of 8.9%, thus confirming the diagnosis of methemoglobinemia. The suites were simple with normalization of the saturation. It is important to know the complications of the injection of methylene blue in order to prevent them and ensure adequate monitoring for the patients.

摘要

亚甲蓝用于在腹腔镜检查期间检查输卵管通畅性。我们报告了一例 28 岁患者的病例,该患者在腹腔镜检查因不孕而进行的亚甲蓝试验后出现皮肤、粘膜和指甲呈蓝色。血氧饱和度为 82%。患者在重症监护病房住院 48 小时,分光光度分析显示高铁血红蛋白水平为 8.9%,从而确诊为高铁血红蛋白血症。套房很简单,饱和度正常。了解亚甲蓝注射的并发症非常重要,以便预防这些并发症并确保对患者进行充分监测。

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1
The methylene blue test, a risky intervention: A case report.亚甲蓝试验,一项有风险的介入:病例报告。
Tunis Med. 2021;99(5):582-584.
2
Methemoglobinemia induced by methylene blue pertubation during laparoscopy.腹腔镜检查期间亚甲蓝干扰诱发的高铁血红蛋白血症
Acta Anaesthesiol Scand. 1998 May;42(5):594-5. doi: 10.1111/j.1399-6576.1998.tb05173.x.
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False indication of arterial oxygen desaturation and methemoglobinemia following injection of methylene blue in urological surgery.泌尿外科手术中注射亚甲蓝后动脉血氧饱和度假性降低和高铁血红蛋白血症
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本文引用的文献

1
Fatal pulmonary oedema following laparoscopic chromopertubation.腹腔镜输卵管通液术后致命性肺水肿
Natl Med J India. 2006 Mar-Apr;19(2):78-9.
2
Acquired methemoglobinemia: a retrospective series of 138 cases at 2 teaching hospitals.获得性高铁血红蛋白血症:两家教学医院138例回顾性研究系列病例
Medicine (Baltimore). 2004 Sep;83(5):265-273. doi: 10.1097/01.md.0000141096.00377.3f.
3
Methemoglobinemia following chromopertubation in treated pelvic tuberculosis.经治疗的盆腔结核行输卵管插管术后高铁血红蛋白血症
Int J Gynaecol Obstet. 2002 Apr;77(1):41-2. doi: 10.1016/s0020-7292(01)00574-4.
4
Allergic reactions to isosulfan blue during sentinel node biopsy--a common event.前哨淋巴结活检术中对异硫蓝的过敏反应——常见情况。
Surgery. 2001 Sep;130(3):439-42. doi: 10.1067/msy.2001.116407.
5
Methemoglobinemia induced by methylene blue pertubation during laparoscopy.腹腔镜检查期间亚甲蓝干扰诱发的高铁血红蛋白血症
Acta Anaesthesiol Scand. 1998 May;42(5):594-5. doi: 10.1111/j.1399-6576.1998.tb05173.x.
6
Inflammatory peritonitis with ascites after methylene blue dye chromopertubation during diagnostic laparoscopy.诊断性腹腔镜检查期间亚甲蓝染料输卵管通液术后伴有腹水的炎性腹膜炎。
J Am Assoc Gynecol Laparosc. 1995 Aug;2(4):483-5. doi: 10.1016/s1074-3804(05)80076-3.
7
Pulmonary edema following intrauterine methylene blue injection.宫内注射亚甲蓝后发生肺水肿。
Acta Anaesthesiol Scand. 1996 Mar;40(3):382-4. doi: 10.1111/j.1399-6576.1996.tb04451.x.