Medical College of Soochow University, Suzhou, Jiangsu Province, China.
Guangji Hospital Affiliated to Soochow University, Suzhou, Jiangsu Province, China.
Global Health. 2020 Dec 18;16(1):119. doi: 10.1186/s12992-020-00644-6.
The pattern of fatigue in older psychiatric patients during the COVID-19 outbreak was unknown. This study examined the prevalence of fatigue and its association with overall quality of life (overall QOL) in clinically stable older patients with psychiatric disorders during the COVID-19 outbreak.
This was a multicenter, cross-sectional study. Fatigue, depressive symptoms, pain, insomnia symptoms, and overall QOL were assessed with standardized instruments.
A total of 1063 patients were recruited. The prevalence of fatigue was 47.1% (95%CI: 44.1-50.1%). An analysis of covariance revealed that overall QOL was significantly lower in patients with fatigue compared to those without (P = 0.011). A multiple logistic regression analysis revealed that more severe depressive symptoms (OR = 1.15, P < 0.001), insomnia symptoms (OR = 1.08, P < 0.001) and pain (OR = 1.43, P < 0.001) were significantly associated with fatigue.
Fatigue is common among clinically stable older patients with psychiatric disorders during the COVID-19 outbreak. Considering its negative impact on overall QOL, regular assessment of fatigue and appropriate treatment warrant attention in this subpopulation.
在 COVID-19 疫情期间,老年精神科患者的疲劳模式尚不清楚。本研究旨在探讨在 COVID-19 疫情期间,临床稳定的老年精神障碍患者疲劳的发生率及其与总体生活质量(总体 QOL)的关系。
这是一项多中心、横断面研究。使用标准化工具评估疲劳、抑郁症状、疼痛、失眠症状和总体 QOL。
共招募了 1063 名患者。疲劳的患病率为 47.1%(95%CI:44.1-50.1%)。协方差分析显示,有疲劳症状的患者的总体 QOL 明显低于无疲劳症状的患者(P=0.011)。多因素逻辑回归分析显示,更严重的抑郁症状(OR=1.15,P<0.001)、失眠症状(OR=1.08,P<0.001)和疼痛(OR=1.43,P<0.001)与疲劳显著相关。
在 COVID-19 疫情期间,临床稳定的老年精神障碍患者中疲劳很常见。鉴于疲劳对总体 QOL 的负面影响,在该亚人群中需要定期评估疲劳并进行适当的治疗。