• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Low back pain as an unusual presentation in a child with acute lymphoblastic leukaemia.儿童急性淋巴细胞白血病以腰痛为表现不常见。
BMJ Case Rep. 2022 Mar 4;15(3):e242843. doi: 10.1136/bcr-2021-242843.
2
Back pain and vertebral compression: an unusual presentation of childhood acute lymphoblastic leukemia.背痛与椎体压缩:儿童急性淋巴细胞白血病的一种不寻常表现。
Mymensingh Med J. 2010 Jan;19(1):130-6.
3
Low back pain in a child--a diagnostic dilemma. Acute lymphoblastic leukaemia causing osteopenia.儿童腰痛——诊断难题。急性淋巴细胞白血病导致骨质减少。
Postgrad Med J. 2001 May;77(907):342, 349-50. doi: 10.1136/pmj.77.907.342.
4
Acute lymphoblastic leukaemia with osteolytic bone lesions: diagnostic dilemma.伴有溶骨性骨病变的急性淋巴细胞白血病:诊断困境
BMJ Case Rep. 2018 Aug 11;2018:bcr-2018-225008. doi: 10.1136/bcr-2018-225008.
5
Acute lymphoblastic leukaemia presenting with severe hypercalcaemia.以严重高钙血症为表现的急性淋巴细胞白血病。
Mymensingh Med J. 2011 Jan;20(1):134-7.
6
Bone marrow necrosis preceding infantile acute lymphoblastic leukaemia.婴儿急性淋巴细胞白血病之前的骨髓坏死。
Malays J Pathol. 2007 Dec;29(2):113-7.
7
Acute lymphocytic leukaemia presenting as a metabolic bone disease.以代谢性骨病形式出现的急性淋巴细胞白血病。
BMJ Case Rep. 2013 Mar 15;2013:bcr2013008758. doi: 10.1136/bcr-2013-008758.
8
Sacroiliitis as an initial presentation of acute lymphoblastic leukaemia.骶髂关节炎作为急性淋巴细胞白血病的首发表现。
Acta Clin Belg. 2010 May-Jun;65(3):197-9. doi: 10.1179/acb.2010.041.
9
An unusual orthopaedic presentation of acute lymphoblastic leukemia.急性淋巴细胞白血病的一种不寻常的骨科表现。
J Pediatr Orthop B. 2003 Jul;12(4):292-4. doi: 10.1097/01.bpb.0000049580.53117.2c.
10
Therapy-related myeloid neoplasm in an 18-year-old boy with B-lymphoblastic leukemia.一名患有B淋巴细胞白血病的18岁男孩的治疗相关髓系肿瘤
Exp Mol Pathol. 2017 Dec;103(3):263-266. doi: 10.1016/j.yexmp.2017.11.007. Epub 2017 Nov 16.

引用本文的文献

1
Common differential diagnosis of low back pain in contemporary medical practice: a narrative review.当代医学实践中腰痛的常见鉴别诊断:一项叙述性综述。
Front Med (Lausanne). 2024 Feb 6;11:1366514. doi: 10.3389/fmed.2024.1366514. eCollection 2024.

本文引用的文献

1
Back pain: An unusual manifestation of acute lymphoblastic leukemia - A case report and review of literature.背痛:急性淋巴细胞白血病的一种不寻常表现——一例病例报告及文献复习
J Family Med Prim Care. 2017 Jul-Sep;6(3):657-659. doi: 10.4103/2249-4863.222020.
2
Low backache in adults as an initial presentation of acute lymphoblastic leukemia.成人急性淋巴细胞白血病首发表现为腰痛。
J Family Med Prim Care. 2017 Apr-Jun;6(2):434-436. doi: 10.4103/2249-4863.220014.
3
Bone involvement at diagnosis as a predictive factor in children with acute lymphoblastic leukemia.诊断时的骨骼受累作为儿童急性淋巴细胞白血病的一个预测因素。
Hippokratia. 2016 Jul-Sep;20(3):227-230.
4
High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy.治疗开始后 12 个月,急性淋巴细胞白血病患儿的椎体骨折发生率较高。
J Clin Oncol. 2012 Aug 1;30(22):2760-7. doi: 10.1200/JCO.2011.40.4830. Epub 2012 Jun 25.
5
Back pain and vertebral compression: an unusual presentation of childhood acute lymphoblastic leukemia.背痛与椎体压缩:儿童急性淋巴细胞白血病的一种不寻常表现。
Mymensingh Med J. 2010 Jan;19(1):130-6.
6
Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program.新诊断的急性淋巴细胞白血病儿童中的椎体骨折进展:加拿大儿童人群类固醇相关骨质疏松症(STOPP)研究项目的结果
J Bone Miner Res. 2009 Jul;24(7):1326-34. doi: 10.1359/jbmr.090202.
7
Multiple vertebral collapse as a presentation of childhood acute lymphoblastic leukaemia.多发性椎体塌陷作为儿童急性淋巴细胞白血病的一种表现形式。
Br J Haematol. 2009 Mar;144(5):627. doi: 10.1111/j.1365-2141.2008.07396.x. Epub 2008 Oct 18.
8
Musculoskeletal manifestations in pediatric acute leukemia.小儿急性白血病的肌肉骨骼表现
J Pediatr Orthop. 2008 Jan-Feb;28(1):20-8. doi: 10.1097/BPO.0b13e31815ff350.
9
Marked osteoporosis and spontaneous vertebral fractures in children: don't forget, it could be leukemia.儿童明显的骨质疏松症和自发性椎体骨折:别忘了,可能是白血病。
Med Pediatr Oncol. 2003 Nov;41(5):450-1. doi: 10.1002/mpo.10295.
10
Vertebral compression fractures in acute lymphoblastic leukaemia and remodelling after treatment.急性淋巴细胞白血病中的椎体压缩性骨折及治疗后的重塑
Arch Dis Child. 2001 Dec;85(6):492-3. doi: 10.1136/adc.85.6.492.

儿童急性淋巴细胞白血病以腰痛为表现不常见。

Low back pain as an unusual presentation in a child with acute lymphoblastic leukaemia.

机构信息

Department of Clinical Epidemiology, University of the Philippines, Manila, Philippines

Department of Pediatrics, Batangas Medical Center, Batangas, Philippines.

出版信息

BMJ Case Rep. 2022 Mar 4;15(3):e242843. doi: 10.1136/bcr-2021-242843.

DOI:10.1136/bcr-2021-242843
PMID:35246428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8900049/
Abstract

Acute leukaemia is the most common childhood cancer. The clinical presentation of acute leukaemia includes fever, pallor, bleeding tendencies, hepatosplenomegaly, lymphadenopathy and bone pains. This case is about a 7-year-old boy who presented with 2 months of progressive low back pain after jumping into the sea. Radiologic workup showed compression fractures in the T6-L5 regions of the spine. Trauma and osteogenesis imperfecta were considered initially until the patient developed the classic features of leukaemia. Analysis of the bone marrow aspirate, 2 months after the sea incident, revealed B cell acute lymphoblastic leukaemia (ALL). The low back pain subsided after a week of chemotherapy. A symptom that involves bone pain in a child needs thorough evaluation because a delay in diagnosis affects the outcome of treatment. ALL has been lingering at the time of his accident and this has caused weakening of his spine that resulted in much more severe injury than would have occurred in the absence of the ALL.

摘要

急性白血病是最常见的儿童癌症。急性白血病的临床表现包括发热、苍白、出血倾向、肝脾肿大、淋巴结病和骨痛。本病例为 7 岁男孩,在跳入海中后 2 个月出现进行性腰痛。影像学检查显示 T6-L5 脊柱区域的压缩性骨折。最初考虑了创伤和成骨不全症,直到患者出现白血病的典型特征。在海难发生后 2 个月对骨髓抽吸物进行分析,显示 B 细胞急性淋巴细胞白血病(ALL)。化疗一周后,腰痛缓解。涉及儿童骨痛的症状需要进行彻底评估,因为诊断延迟会影响治疗效果。ALL 在他发生事故时一直存在,这导致他的脊柱变弱,导致比没有 ALL 时更严重的损伤。