神经外科学会关于细胞减灭手术在成人进展性胶质母细胞瘤治疗中作用的系统评价和循证指南更新。
Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of cytoreductive surgery in the management of progressive glioblastoma in adults.
机构信息
Department of Neurological Surgery, George Washington University, 900 23rd St NW, Washington, DC, 20037, USA.
Department of Neurosurgery, West Virginia University Rockefeller Neuroscience Institute, Martinsburg, WV, USA.
出版信息
J Neurooncol. 2022 Jun;158(2):167-177. doi: 10.1007/s11060-021-03881-w. Epub 2022 Mar 4.
QUESTION
In patients with previously diagnosed glioblastoma who are suspected of experiencing progression, does repeat cytoreductive surgery improve progression free survival or overall survival compared to alternative interventions?
TARGET POPULATION
These recommendations apply to adults with previously diagnosed glioblastoma who are suspected of experiencing progression of the neoplastic process and are amenable to surgical resection.
RECOMMENDATION
Level II: Repeat cytoreductive surgery is recommended in progressive glioblastoma patients to improve overall survival.
问题
对于疑似进展的先前诊断为胶质母细胞瘤的患者，与其他干预措施相比，重复肿瘤切除术是否能改善无进展生存期或总生存期？
目标人群
本推荐意见适用于先前诊断为胶质母细胞瘤且疑似肿瘤进展、适合手术切除的成人患者。
推荐意见
Ⅱ级：对于进展性胶质母细胞瘤患者，建议行重复肿瘤切除术以提高总生存期。
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