Yoon Ji Ha, Baek Eun Joo, Park Eun Joo, Kim Kwang Ho
Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Dermatol Ther. 2022 May;35(5):e15419. doi: 10.1111/dth.15419. Epub 2022 Mar 12.
Benign lichenoid keratosis is one of the most common skin lesions that develop on the faces of middle-aged women. This study aimed to find an effective treatment method for benign lichenoid keratosis. A total of 49 patients, who had a positive diagnosis during 2010-2018, were enrolled in the study. An Investigator's Global Assessment of the lesion was done using the 5-point visual analog scale to evaluate treatment efficacy. After excluding subjects who did not have a follow-up photograph, 38 subjects were given an Investigator's Global Assessment score. Combination therapy using laser and a topical agent was useful in the management of benign lichenoid keratosis on the face. Ablative laser was effective for immediate improvement of the lesion, whereas non-ablative laser was also useful and showed several benefits over ablative laser. Optimal treatment should be decided after considering the patient's preference, compliance with treatment regimen, and skin type.
良性苔藓样角化病是中年女性面部最常见的皮肤病变之一。本研究旨在寻找一种治疗良性苔藓样角化病的有效方法。共有49例在2010 - 2018年期间确诊的患者纳入本研究。使用5分视觉模拟量表进行研究者对病变的整体评估，以评估治疗效果。在排除没有随访照片的受试者后，38名受试者获得了研究者的整体评估分数。激光与外用药物联合治疗对面部良性苔藓样角化病的治疗有效。剥脱性激光可使病变立即改善，而非剥脱性激光也有效，且比剥脱性激光有若干优势。应在考虑患者偏好、对治疗方案的依从性和皮肤类型后决定最佳治疗方法。
