School of Paramedics and Allied Health Sciences, Centurion University of Technology and Management, Sitapur, Odisha, India.
School of Applied Sciences, Centurion University of Technology and Management, Sitapur, Odisha, India.
Appl Biochem Biotechnol. 2022 Jun;194(6):2796-2830. doi: 10.1007/s12010-021-03711-9. Epub 2022 Mar 5.
In every age group, urinary tract infection (UTI) is found as a major recurrence infectious disorder. Bio-films produced by bacteria perform a vital role in causing infection in the tract of the urinary system, leading to recurrences and relapses. The purpose of this review is to present the role and mechanism of bio-film producing MDR Gram-negative bacteria causing UTI, their significance, additionally the challenges for remedy and prevention of catheter-associated UTI. This work appreciates a new understanding of bio-film producers which are having multi-drug resistance capability and focuses on the effect and control of bio-film producing uropathogenic bacteria related to catheterization. We have tried to analyze approaches to target bio-film and reported phytochemicals with anti-bio-film activity also updated on anti-bio-film therapy.
在每个年龄段，尿路感染（UTI）都被发现是一种主要的复发性传染病。细菌产生的生物膜在引起泌尿系统感染方面起着至关重要的作用，导致复发和反复感染。本综述的目的是介绍产生生物膜的耐多药革兰氏阴性菌引起 UTI 的作用和机制、它们的意义，以及治疗和预防与导管相关的 UTI 的挑战。这项工作对具有多药耐药能力的生物膜生产者有了新的认识，并侧重于与导管插入相关的产生物膜的尿路致病性细菌的影响和控制。我们试图分析针对生物膜的方法，并报告具有抗生物膜活性的植物化学物质，同时更新抗生物膜治疗。
