Li Chenxu, Zhao Pengli, Shao Qi, Chen Wenbin, Huang Shucheng, Wang Xueying, Zhang Cai, He Lei
Henan International Joint Laboratory of Animal Welfare and Health Breeding, Henan University of Science and Technology, Luoyang, China.
College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
J Anim Physiol Anim Nutr (Berl). 2023 Jan;107(1):136-146. doi: 10.1111/jpn.13692. Epub 2022 Mar 5.
The purpose of this study was to evaluate the effects of dietary Glycyrrhiza polysaccharide (GCP) on growth performance, blood parameters and immunity in weaned piglets. A total of 240 (10.33 ± 0.62 kg body weight) 35-day-old (Duroc × Landrace × White) weaned piglets were randomly assigned to four dietary treatments, with six replicate pens per treatment and 10 piglets per pen (five males and five females). The dietary treatments continued for 21 days and comprised a basal diet supplemented with 0 (control group), 500, 1000 and 2000 mg/kg GCP. The results showed that the inclusion of 1000 and 2000 mg/kg GCP increased the average daily gain and decreased the feed conversion rate compared with the control group (p < 0.05). The piglets treated with 500 and 1000 mg/kg GCP had a lower diarrhoeal incidence than the control group (p < 0.05). Moreover, supplementation with 1000 mg/kg GCP increased the counts of white blood cells, neutrophils, red blood cells, and platelets, and elevated alkaline phosphatase, total protein, globulin, glucose, triglyceride, immunoglobulin A, immunoglobulin G, and total antioxidant capacity levels (p < 0.05), and decreased malondialdehyde content compare with the control group (p < 0.05). In addition, relative to the control group, piglets fed 500 and 1000 mg/kg GCP had significantly lower expression of interleukin-6 mRNA in spleen (p < 0.05). Our results indicate that dietary supplementation with GCP can improve growth performance, blood parameters and immunity in weaned piglets. Our study suggests that adding 1000 mg/kg GCP to the diet had the most beneficial effect.
本研究的目的是评估日粮中甘草多糖（GCP）对断奶仔猪生长性能、血液参数和免疫力的影响。选取240头35日龄（杜洛克×长白×大白）断奶仔猪（体重10.33±0.62 kg），随机分为4组日粮处理，每组6个重复栏，每栏10头仔猪（5头公猪和5头母猪）。日粮处理持续21天，包括基础日粮分别添加0（对照组）、500、1000和2000 mg/kg GCP。结果表明，与对照组相比，添加1000和2000 mg/kg GCP提高了平均日增重，降低了饲料转化率（p<0.05）。添加500和1000 mg/kg GCP处理的仔猪腹泻发生率低于对照组（p<0.05）。此外，添加1000 mg/kg GCP增加了白细胞、中性粒细胞、红细胞和血小板计数，提高了碱性磷酸酶、总蛋白、球蛋白、葡萄糖、甘油三酯、免疫球蛋白A、免疫球蛋白G和总抗氧化能力水平（p<0.05），与对照组相比丙二醛含量降低（p<0.05）。另外，与对照组相比，饲喂500和1000 mg/kg GCP的仔猪脾脏中白细胞介素-6 mRNA表达显著降低（p<0.05）。我们的结果表明，日粮中添加GCP可改善断奶仔猪的生长性能、血液参数和免疫力。我们的研究表明，日粮中添加1000 mg/kg GCP具有最有益的效果。
