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通过磁共振波谱法测量运动肌肉代谢。

Exercise muscle metabolism measured by magnetic resonance spectroscopy.

作者信息

Inch W R, Serebrin B, Taylor A W, Thompson R T

出版信息

Can J Appl Sport Sci. 1986 Jun;11(2):60-5.

PMID:3524887
Abstract

Nuclear magnetic resonance imaging (MRI) is a technique which gives body images in much the same way as X-ray tomography. Most images are produced from signals of mobile hydrogen atoms in the tissues. Since bone contains few such atoms the images do not show bone material but allow marrow to be observed. Recently the technique has been extended to include spectroscopy of atoms of 31P, 13C and several others important in cell and tissue metabolism. The technique which uses a radiofrequency surface coil placed over the tissue of interest, is called topical magnetic resonance spectroscopy (MRS). Magnetic resonance spectroscopy which measures phosphorus nuclei can be used to study phosphorus in muscle. The same instrument can be used to study hydrogen density distribution. It can monitor muscle metabolism during exercise and muscle energetics can thus be evaluated. MRS gives a more accurate picture of the in vivo proportions of high energy phosphates than conventional biochemical analysis, which requires muscle biopsy, it can be used to monitor living tissue in a non-destructive way.

摘要

核磁共振成像(MRI)是一种以与X射线断层扫描非常相似的方式生成人体图像的技术。大多数图像是由组织中移动氢原子的信号产生的。由于骨骼中此类原子很少,图像无法显示骨质,但可以观察到骨髓。最近,该技术已扩展到包括对31P、13C以及其他几种对细胞和组织代谢很重要的原子进行光谱分析。使用放置在感兴趣组织上方的射频表面线圈的技术称为局部磁共振波谱(MRS)。测量磷核的磁共振波谱可用于研究肌肉中的磷。同一仪器可用于研究氢密度分布。它可以监测运动期间的肌肉代谢,从而评估肌肉能量学。与需要进行肌肉活检的传统生化分析相比,MRS能更准确地呈现体内高能磷酸盐的比例,它可以以非破坏性的方式用于监测活组织。

相似文献

1
Exercise muscle metabolism measured by magnetic resonance spectroscopy.通过磁共振波谱法测量运动肌肉代谢。
Can J Appl Sport Sci. 1986 Jun;11(2):60-5.
2
Phosphorus nuclear magnetic resonance: a non-invasive technique for the study of muscle bioenergetics during exercise.磷核磁共振:一种用于研究运动期间肌肉生物能量学的非侵入性技术。
Med Sci Sports Exerc. 1987 Aug;19(4):410-20.
3
Phosphorus nuclear magnetic resonance: a non-invasive technique for the study of muscle bioenergetics during exercise.磷核磁共振:一种用于研究运动期间肌肉生物能量学的非侵入性技术。
Med Sci Sports Exerc. 1993 Jun;25(6):656-66.
4
Muscle energy metabolism in human phosphofructokinase deficiency as recorded by 31P nuclear magnetic resonance spectroscopy.
Ann Neurol. 1987 Jul;22(1):46-51. doi: 10.1002/ana.410220112.
5
Use of magnetic resonance in body composition studies: applications to research on caloric restriction and exercise.磁共振成像在身体成分研究中的应用:对热量限制与运动研究的应用
Coll Antropol. 1998 Dec;22(2):385-92.
6
The current status of magnetic resonance spectroscopy--basic and clinical aspects.磁共振波谱学的现状——基础与临床方面
West J Med. 1985 Dec;143(6):773-81.
7
31P-NMR studies on an animal model of human defective muscle glycolysis.
Muscle Nerve. 1986 Feb;9(2):138-43. doi: 10.1002/mus.880090205.
8
Observation of intramyocellular lipids by 1H-magnetic resonance spectroscopy.采用氢质子磁共振波谱技术观察肌细胞内脂质。
Ann N Y Acad Sci. 2000 May;904:25-31.
9
A model for in vivo serial investigation of hepatic metabolism using 31P nuclear magnetic resonance spectroscopy.一种使用31P核磁共振波谱进行肝脏代谢体内连续研究的模型。
In Vivo. 1991 Mar-Apr;5(2):179-83.
10
Depletion of high energy phosphates implicates post-exercise mortality in carp and trout; an in vivo 31P-NMR study.高能磷酸盐的消耗与鲤鱼和鳟鱼运动后的死亡率有关;一项体内31P-NMR研究。
Comp Biochem Physiol A Mol Integr Physiol. 2008 Jan;149(1):98-108. doi: 10.1016/j.cbpa.2007.10.014. Epub 2007 Nov 6.

引用本文的文献

1
31P-nuclear magnetic resonance spectroscopy study of the time course of energy metabolism during exercise and recovery.运动及恢复过程中能量代谢时间进程的31P-核磁共振波谱研究
Eur J Appl Physiol Occup Physiol. 1993;66(6):494-9. doi: 10.1007/BF00634298.