Inch W R, Serebrin B, Taylor A W, Thompson R T
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Nuclear magnetic resonance imaging (MRI) is a technique which gives body images in much the same way as X-ray tomography. Most images are produced from signals of mobile hydrogen atoms in the tissues. Since bone contains few such atoms the images do not show bone material but allow marrow to be observed. Recently the technique has been extended to include spectroscopy of atoms of 31P, 13C and several others important in cell and tissue metabolism. The technique which uses a radiofrequency surface coil placed over the tissue of interest, is called topical magnetic resonance spectroscopy (MRS). Magnetic resonance spectroscopy which measures phosphorus nuclei can be used to study phosphorus in muscle. The same instrument can be used to study hydrogen density distribution. It can monitor muscle metabolism during exercise and muscle energetics can thus be evaluated. MRS gives a more accurate picture of the in vivo proportions of high energy phosphates than conventional biochemical analysis, which requires muscle biopsy, it can be used to monitor living tissue in a non-destructive way.
核磁共振成像(MRI)是一种以与X射线断层扫描非常相似的方式生成人体图像的技术。大多数图像是由组织中移动氢原子的信号产生的。由于骨骼中此类原子很少,图像无法显示骨质,但可以观察到骨髓。最近,该技术已扩展到包括对31P、13C以及其他几种对细胞和组织代谢很重要的原子进行光谱分析。使用放置在感兴趣组织上方的射频表面线圈的技术称为局部磁共振波谱(MRS)。测量磷核的磁共振波谱可用于研究肌肉中的磷。同一仪器可用于研究氢密度分布。它可以监测运动期间的肌肉代谢,从而评估肌肉能量学。与需要进行肌肉活检的传统生化分析相比,MRS能更准确地呈现体内高能磷酸盐的比例,它可以以非破坏性的方式用于监测活组织。