Department of Radio-diagnosis, Maulana Azad Medical College, New Delhi, India.
Department of Radio-diagnosis, Maulana Azad Medical College, New Delhi, India.
Curr Probl Diagn Radiol. 2022 Sep-Oct;51(5):798-805. doi: 10.1067/j.cpradiol.2022.02.001. Epub 2022 Feb 7.
Recent pandemic of COVID19 infection has witnessed a re-emergence of invasive fungal sinusitis especially of the Mucor species, which has been a rare entity in the pre covid era. Covid associated mucormycosis (CAM) is one of the dreaded and fatal complications which has surfaced up and early diagnosis is critical for management and survival .It is identified to affect both subset of patients, those with active COVID-19 infection and those who have recovered from the disease in the last 4-6 weeks. Imaging features suggestive of early invasion with supportive imaging examples and relevance of these findings in clinical decision making is presented.
This paper reviews the various imaging signs of early invasion in CAM A comprehensive checklist for clinically relevant and quick reporting is also presented.
Emphysematous or ulcerative mucosal changes in the nasal cavity is an early imaging feature of CAM. Periantral soft tissue and soft tissue within the pterygopalatine fossa are important imaging signs to indicate extrasinus invasion. Disease within pterygopalatine fossa may lead to multidirectional spread and is an important check site. These findings are seen even in absence of bony erosions owing to the neurovascular spread of disease. Intra orbital and intracranial extensions were found to be fairly common and must be sought for.
The knowledge of early subtle signs of CAM on imaging can aid in prompt diagnosis of this fatal entity in the pertinent clinical setting. Imaging signs of spread of disease and delineation of its extent as inferred from CT imaging aids in prognosis and appropriate surgical management.
最近的 COVID19 感染大流行见证了侵袭性真菌性鼻窦炎的再次出现,特别是毛霉属物种,这在新冠疫情前是一种罕见的实体。与新冠相关的毛霉菌病(CAM)是一种可怕且致命的并发症之一,已经出现,早期诊断对于管理和生存至关重要。它被认为会影响两组患者,一组是患有活动性 COVID-19 感染的患者,另一组是在过去 4-6 周内从疾病中康复的患者。本文介绍了 CAM 早期侵袭的各种影像学特征,以及支持这些影像学特征的影像学示例,以及这些发现对临床决策的相关性。
本文回顾了 CAM 中早期侵袭的各种影像学征象,还提出了一份临床相关且快速报告的综合检查表。
鼻腔的气肿性或溃疡性黏膜改变是 CAM 的早期影像学特征。眶周软组织和翼腭窝内的软组织是表明鼻窦外侵袭的重要影像学征象。翼腭窝内的疾病可能导致多方向传播,是一个重要的检查部位。即使没有骨侵蚀,由于疾病的神经血管传播,也可以看到这些发现。发现眼眶内和颅内延伸较为常见,必须寻找这些病变。
在相关临床环境中,对 CAM 的早期细微影像学特征的了解可以帮助快速诊断这种致命实体。疾病传播的影像学征象及其从 CT 成像推断的范围可以帮助预测和进行适当的手术治疗。