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叙利亚金黄地鼠部分肝切除术后外分泌腺和内分泌腺胰腺中的DNA合成

DNA synthesis in exocrine and endocrine pancreas after partial hepatectomy in Syrian golden hamsters.

作者信息

Rao M S, Subbarao V

出版信息

Experientia. 1986 Jul 15;42(7):833-4. doi: 10.1007/BF01941543.

DOI:10.1007/BF01941543
PMID:3525211
Abstract

3H-thymidine autoradiography showed an enhanced DNA synthesis in acinar and islet cells of pancreas after partial hepatectomy in syrian golden hamsters. A significant nuclear labeling index of acinar cells was observed between 48 and 84 h and reached control levels by 120 h. An increased labeling index of islet cells was also observed, however, this increase was not statistically significant. These results indicate growth factor(s) produced after partial hepatectomy is capable of inducing DNA synthesis in pancreas.

摘要

3H-胸腺嘧啶核苷放射自显影显示,叙利亚金黄地鼠部分肝切除术后胰腺腺泡细胞和胰岛细胞中的DNA合成增强。在48至84小时之间观察到腺泡细胞有显著的核标记指数,到120小时达到对照水平。也观察到胰岛细胞的标记指数增加,然而,这种增加没有统计学意义。这些结果表明,部分肝切除术后产生的生长因子能够诱导胰腺中的DNA合成。

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本文引用的文献

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LABELLING OF DNA AND CELL DIVISION IN SO CALLED NON-DIVIDING TISSUES.所谓非分裂组织中DNA的标记与细胞分裂
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Induction and origin of hepatocytes in rat pancreas.大鼠胰腺中肝细胞的诱导与起源
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8
Regeneration of Syrian golden hamster pancreas and covalent binding of N-nitroso-2,6-[3H]dimethylmorpholine.叙利亚金黄地鼠胰腺的再生以及N-亚硝基-2,6-[³H]二甲基吗啉的共价结合
Cancer Res. 1981 Mar;41(3):1051-7.
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Pancreatic acinar cell regeneration. IV. Regeneration after resection.胰腺腺泡细胞再生。IV. 切除术后的再生
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