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An approach to a patient with suspected meat allergy due to underlying alpha-Gal syndrome in a resource-limited setting.

作者信息

Vanegas Emanuel, Felix Miguel, Farfán Bajaña María José, Robles-Velasco Karla, Panchana Lascano Matias, Crespo Shijin Carolina, Hinostroza Logroño Romina, Greiding Leonardo, Cherrez-Ojeda Iván

机构信息

Respiralab Research Group, Guayaquil, Ecuador.

Universidad de Especialidades Espíritu Santo, Samborondón, Ecuador.

出版信息

JAAD Case Rep. 2022 Feb 1;21:173-175. doi: 10.1016/j.jdcr.2022.01.025. eCollection 2022 Mar.

DOI:10.1016/j.jdcr.2022.01.025
PMID:35252518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8888892/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ddc/8888892/f96abe283bcd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ddc/8888892/9e032430f750/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ddc/8888892/f96abe283bcd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ddc/8888892/9e032430f750/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ddc/8888892/f96abe283bcd/gr2.jpg

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An approach to a patient with suspected meat allergy due to underlying alpha-Gal syndrome in a resource-limited setting.在资源有限的情况下，针对疑似因潜在的α-半乳糖综合征而对肉类过敏患者的一种处理方法。
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Meat allergy associated with galactosyl-α-(1,3)-galactose (α-Gal)-Closing diagnostic gaps by anti-α-Gal IgE immune profiling.肉过敏与半乳糖-α-(1,3)-半乳糖（α-Gal）有关——通过抗-α-Gal IgE 免疫分析来填补诊断空白。
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引用本文的文献

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本文引用的文献

1
Diagnosis & management of alpha-gal syndrome: lessons from 2,500 patients.α-半乳糖苷综合征的诊断与管理：2500 例患者的经验教训。
Expert Rev Clin Immunol. 2020 Jul;16(7):667-677. doi: 10.1080/1744666X.2020.1782745. Epub 2020 Jul 8.
2
Challenges of managing food allergy in the developing world.发展中世界食物过敏管理面临的挑战。
World Allergy Organ J. 2019 Dec 2;12(11):100089. doi: 10.1016/j.waojou.2019.100089. eCollection 2019 Nov.
3
Tick Bite Linked to Red Meat Allergy.蜱虫叮咬与红肉过敏有关。
JAMA. 2018 Jan 23;319(4):332. doi: 10.1001/jama.2017.20802.
4
Diagnosis of red meat allergy with antigen-specific IgE tests in serum.采用血清中抗原特异性IgE检测诊断红肉过敏。
J Allergy Clin Immunol. 2017 Aug;140(2):608-610.e5. doi: 10.1016/j.jaci.2017.01.032. Epub 2017 Mar 6.
5
IgE production to α-gal is accompanied by elevated levels of specific IgG1 antibodies and low amounts of IgE to blood group B.针对α-半乳糖的 IgE 产生伴随着特异性 IgG1 抗体水平升高和对血型 B 的 IgE 量低。
PLoS One. 2013;8(2):e55566. doi: 10.1371/journal.pone.0055566. Epub 2013 Feb 4.
6
Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-alpha-1,3-galactose.对于具有针对半乳糖-α-1,3-半乳糖的IgE抗体的患者，食用红肉后出现迟发性过敏反应、血管性水肿或荨麻疹。
J Allergy Clin Immunol. 2009 Feb;123(2):426-33. doi: 10.1016/j.jaci.2008.10.052. Epub 2008 Dec 13.
7
The alpha-gal epitope and the anti-Gal antibody in xenotransplantation and in cancer immunotherapy.异种移植和癌症免疫治疗中的α-半乳糖表位与抗半乳糖抗体
Immunol Cell Biol. 2005 Dec;83(6):674-86. doi: 10.1111/j.1440-1711.2005.01366.x.
8
IgE antibody response to vertebrate meat proteins including tropomyosin.对包括原肌球蛋白在内的脊椎动物肉类蛋白的IgE抗体反应。
Ann Allergy Asthma Immunol. 1999 Nov;83(5):399-405. doi: 10.1016/S1081-1206(10)62837-2.
9
Clinical reactivity to beef in children allergic to cow's milk.对牛奶过敏儿童对牛肉的临床反应性。
J Allergy Clin Immunol. 1997 Mar;99(3):293-300. doi: 10.1016/s0091-6749(97)70045-9.