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蜱叮咬和红肉过敏导致的α-半乳糖特异性IgE阳性:土耳其首例病例报告。

Alpha gal specific IgE positivity due to tick bites and red meat allergy: the first case report in Turkey.

作者信息

Keleş Şennur, Gündüz Mehmet

机构信息

Department of Pediatric Allergy and Immunology, University of Health Sciences Antalya Training and Research Hospital, Antalya.

Department of Pediatrics, Division of Neonatology, Bağcılar Medipol Mega University Hospital, İstanbul.

出版信息

Turk J Pediatr. 2019;61(4):615-617. doi: 10.24953/turkjped.2019.04.023.

Abstract

Keleş Ş, Gündüz M. Alpha gal specific IgE positivity due to tick bites and red meat allergy: the first case report in Turkey. Turk J Pediatr 2019; 61: 615-617. Galactose-alpha-1,3-galactose is a carbohydrate moiety found in the cell membranes of many organisms, commonly known as alpha-gal (α-Gal). This oligosaccharide is not found in the group of primates in which humans are involved. It has been found that α-Gal plays a key role in delayed IgE-mediated red meat allergy and this allergen is triggered by tick bites. Here we present a 7-year-old boy with alpha-gal allergy from Turkey.

摘要

凯莱什·Ş、贡杜兹·M。蜱叮咬所致α-半乳糖特异性IgE阳性与红肉过敏:土耳其首例病例报告。《土耳其儿科学杂志》2019年;61: 615 - 617。半乳糖-α-1,3-半乳糖是一种存在于许多生物体细胞膜中的碳水化合物部分,通常称为α-半乳糖(α-Gal)。这种寡糖在包括人类在内的灵长类动物群体中不存在。已发现α-Gal在迟发性IgE介导的红肉过敏中起关键作用,且这种过敏原由蜱叮咬引发。在此,我们报告一名来自土耳其的7岁α-半乳糖过敏男孩。

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