Catanzano D, Desbals B, Elchinger B
Diabete Metab. 1986 Jun;12(3):130-6.
The young domestic rabbit (2.5 months old) shows seasonal variation in metabolism similar to wild mammal. During the annual seasonal cycle we observed variations in the intensity of lipogenesis in isolated perirenal adipocytes; fatty acid synthesis, which uses acetate as a precursor rather than glucose, reaches a maximum in winter and a minimum in spring. The magnitude of the glucose induced pancreatic insulin response varies during the annual seasonal cycle and it follows the variations in the lipogenesis cycle; thus, the plasma IRI increase is highest in winter when maximum lipogenesis occurs.
幼龄家兔（2.5月龄）表现出与野生哺乳动物相似的季节性代谢变化。在年度季节性周期中，我们观察到分离的肾周脂肪细胞中脂肪生成强度的变化；以乙酸盐而非葡萄糖为前体的脂肪酸合成在冬季达到最大值，在春季达到最小值。葡萄糖诱导的胰腺胰岛素反应强度在年度季节性周期中有所变化，并且与脂肪生成周期的变化一致；因此，当脂肪生成达到最大值的冬季，血浆IRI升高幅度最大。
