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食用睡鼠(Glis glis L.)葡萄糖负荷后血浆葡萄糖和胰岛素浓度的季节性变化。

Seasonal variations in plasma glucose and insulin concentrations after glucose loading in the edible dormouse (Glis glis L.).

作者信息

Castex C, Donnio R, Sutter B C

出版信息

J Physiol (Paris). 1979;75(3):283-8.

PMID:501667
Abstract

Glucose tolerance tests made in the Edible dormouse showed annual variations in B cell secretory capacity, associated with glucose tolerance changes. 1. During autumn and winter, the B cell is sensitive to glucose, and insulin regulates the high peripheral consumption of this hexose. 2. At the beginning of spring, insulin secretion decreases and glucose tolerance is impaired. In June, the B cell response si low or absent and a poor tolerance to glucose still persists. 3. The variations in B cell activity can be related to changing energy requirements during the year.

摘要

对食用睡鼠进行的葡萄糖耐量试验显示,B细胞分泌能力存在年度变化,这与葡萄糖耐量变化相关。1. 在秋季和冬季,B细胞对葡萄糖敏感,胰岛素调节这种己糖的高外周消耗。2. 在春季开始时,胰岛素分泌减少,葡萄糖耐量受损。在6月,B细胞反应低下或无反应,对葡萄糖的耐受性仍然较差。3. B细胞活性的变化可能与一年中不断变化的能量需求有关。

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引用本文的文献

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Diabetologia. 1982 Apr;22(4):250-3. doi: 10.1007/BF00281300.
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Pancreatic A and B cell stimulation in euthermic and hibernating marmots (Marmota flaviventris): effects of glucose and arginine administration.正常体温和冬眠状态下的黄腹旱獭(Marmota flaviventris)胰腺A细胞和B细胞的刺激:葡萄糖和精氨酸给药的影响
J Comp Physiol B. 1986;156(3):309-14. doi: 10.1007/BF01101092.