Department of Periodontology, Oral and Implant Surgery, Faculty of Medicine, University of Liège, Liège, Belgium.
Dental Biomaterials Research Unit (d-BRU), Faculty of Medicine, University of Liège, Liège, Belgium.
J Prosthodont. 2022 Aug;31(7):585-592. doi: 10.1111/jopr.13504. Epub 2022 May 18.
To evaluate, in a minipig model, the soft tissue integration of four different transmucosal materials, as well as the peri-implant bone remodeling.
A total of 40 implants were placed in five minipigs in a single stage surgery, and two of each of the following abutment materials were used in each animal: (1) titanium (Ti; control), (2) polymethylmethacrylate (PMMA), (3) zirconia (Zi), and (4) veneering ceramic (VC). After a healing period of 3 months, the samples were collected and subjected to nondecalcified histology. The soft tissue dimensions (sulcus, junctional epithelium, and connective tissue attachment) were assessed on each abutment and the distance from the implant margin to first bone-to-implant contact (BIC) was measured.
The mean biological width-characterized by the sum of junctional epithelium and connective tissue measurements-was 3.8 (0.6) mm and no statistically significant difference was found between the four groups (p = 0.41). However, a long junctional epithelium (3.3-3.8 mm) and a very short connective tissue attachment (0.1-0.2 mm) were observed with all abutments. The measured peri-implant bone remodeling was similar in all four groups (p = 0.88).
Within its limitations, this study showed that all tested materials allowed soft tissue integration, consisting of a long junctional epithelium, extending close to the bone level, and a rather short portion of connective tissue.
在小型猪模型中评估四种不同经粘膜材料的软组织整合情况，以及种植体周围骨重塑情况。
在一期手术中，将 40 个种植体植入五头小型猪体内，每只动物使用以下两种基台材料各两个：（1）钛（Ti；对照）、（2）聚甲基丙烯酸甲酯（PMMA）、（3）氧化锆（Zi）和（4）饰面陶瓷（VC）。愈合期 3 个月后，收集样本并进行非脱钙组织学检查。评估每个基台的软组织尺寸（龈沟、结合上皮和结缔组织附着），测量种植体边缘至第一骨-种植体接触（BIC）的距离。
生物学宽度的平均值-由结合上皮和结缔组织测量的总和表示-为 3.8（0.6）mm，四组之间无统计学差异（p = 0.41）。然而，所有基台均观察到长结合上皮（3.3-3.8mm）和非常短的结缔组织附着（0.1-0.2mm）。四个组的测量的种植体周围骨重塑情况相似（p = 0.88）。
在其限制范围内，本研究表明，所有测试材料均允许软组织整合，包括长的结合上皮，延伸至接近骨水平，以及相对较短的结缔组织部分。
