Strasding Malin, Jeong Yuwon, Marchand Laurent, Hicklin Stefan P, Sailer Irena, Sun Minji, Lee Hyeonjong
Division of Fixed Prosthodontics and Biomaterials, University Clinic of Dental Medicine, University of Geneva, Rue Michel-Servet 1, 1211 Geneva, Switzerland.
Department of Prosthodontics, College of Dentistry, Yonsei University, Seoul 03722, Republic of Korea.
Materials (Basel). 2023 Aug 15;16(16):5636. doi: 10.3390/ma16165636.
A prospective multi-center randomized controlled clinical trial was performed to digitally analyze tissue volume changes in immediately and early placed implants with simultaneous bone augmentation restored with two different all-ceramic materials.
A total of 60 patients received 60 bone-level tapered implants (BLT, Straumann AG) immediately (n = 30) or early placed, 8-10 weeks after tooth extraction, (n = 30). Implants were restored with all-ceramic single crowns fabricated out of zirconia (Lava Plus, 3M), or lithium disilicate (E.max CAD, Ivoclar Vivadent AG) bonded to titanium base abutments (Variobase for Cerec, Straumann AG). Impressions were taken at baseline (BL), 6 and 12 months, and STL data were used to define an area of interest (AOI) to analyze peri-implant volume changes and midfacial recessions.
For immediate placement, a mean volume loss of -5.56 mm (±5.83 mm) was found at 6 months, and of -6.62 mm (±6.56 mm) at 12 months. For early placement, a mean volume loss of -1.99 mm (±5.82 mm) at 6 months, and of -3.7 mm (±5.62 mm) at 12 months was found. The differences in volume loss at 12 months between the two implant placement protocols were significant ( = 0.005). In both groups, mean midfacial recessions of 0.48 mm (±0.52) occurred.
A more pronounced peri-implant volume loss can be expected 12 months after immediate implant placement compared with early placement.
进行了一项前瞻性多中心随机对照临床试验，以数字方式分析即刻种植和早期种植的种植体周围组织体积变化，同时采用两种不同全瓷材料进行骨增量修复。
共有60例患者接受了60颗骨水平锥形种植体（BLT，士卓曼公司），其中30例为即刻种植，30例为拔牙后8 - 10周的早期种植。种植体用氧化锆（Lava Plus，3M公司）或二硅酸锂（E.max CAD，义获嘉伟瓦登特公司）制成的全瓷单冠修复，并与钛基台（士卓曼公司的Cerec Variobase）连接。在基线（BL）、6个月和12个月时取印模，使用STL数据定义感兴趣区域（AOI），以分析种植体周围体积变化和面部中部凹陷情况。
即刻种植组在6个月时平均体积损失为 - 5.56 mm（±5.83 mm），12个月时为 - 6.62 mm（±6.56 mm）。早期种植组在6个月时平均体积损失为 - 1.99 mm（±5.82 mm），12个月时为 - 3.7 mm（±5.62 mm）。两种种植方案在12个月时的体积损失差异有统计学意义（P = 0.005）。两组的面部中部平均凹陷均为0.48 mm（±0.52）。
与早期种植相比，即刻种植后12个月种植体周围体积损失更明显。
