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中国东北地区的一项研究表明,健康生活方式的组合与成年人高血压和血脂异常风险之间存在关联。

The association between a combination of healthy lifestyles and the risks of hypertension and dyslipidemia among adults-evidence from the northeast of China.

机构信息

Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, PR China.

Postgraduate Affairs Section, School of Public Health, China Medical University, Shenyang, Liaoning, PR China.

出版信息

Nutr Metab Cardiovasc Dis. 2022 May;32(5):1138-1145. doi: 10.1016/j.numecd.2022.01.020. Epub 2022 Jan 24.

Abstract

BACKGROUND AND AIMS

There is increasing evidence that lifestyle factors play an important role in the development of hypertension and dyslipidemia. However, existing research usually evaluated these risk factors individually (such as physical activity, smoking, drinking, obesity and so on), rather than joint evaluation. The aim of this study was to quantify the association between a combination of a healthy lifestyle and the risk of hypertension and dyslipidemia.

METHODS AND RESULT

A healthy lifestyle score was created based on 4 factors: never smoking, moderate to high-intensive physical activity, no alcohol drinking, and normal body mass index. We calculated the healthy lifestyle score using the cumulative number of health factors for each individual. Also, a multivariate analysis was used to assess the relationship between healthy lifestyle and hypertension and dyslipidemia. Among 6446 participants, 650 (10.08%) had lowest healthy lifestyle score (0) and 627 (9.72%) had highest healthy lifestyle score (4), respectively. The adjustment model indicated that participants with the highest score (score: 4), which integrated the four lifestyles, had significantly lower ORs for hypertension compared with the lowest score (score: 0) (0.21; (95%CI: 0.10, 0.43 P-trend< 0.001)). In the adjustment models, compared with lowest healthy lifestyle score, the ORs of highest healthy lifestyle score was: 0.17; (95%CI: 0.07, 0.42 P-trend<0.001) for dyslipidemia.

CONCLUSION

Hypertension and dyslipidemia were negatively correlated with healthy lifestyle score. Interventions with healthy lifestyle to reduce hypertension, dyslipidemia and promote population health are warranted.

摘要

背景与目的

越来越多的证据表明,生活方式因素在高血压和血脂异常的发生发展中起着重要作用。然而,现有研究通常单独评估这些危险因素(如体力活动、吸烟、饮酒、肥胖等),而不是联合评估。本研究旨在量化健康生活方式组合与高血压和血脂异常风险之间的关联。

方法与结果

根据 4 个因素(从不吸烟、中高强度体力活动、不饮酒和正常体重指数)创建了健康生活方式评分。我们为每个个体计算健康生活方式的累积健康因素数来计算健康生活方式评分。此外,还使用多变量分析评估健康生活方式与高血压和血脂异常之间的关系。在 6446 名参与者中,650 名(10.08%)具有最低的健康生活方式评分(0),627 名(9.72%)具有最高的健康生活方式评分(4)。调整模型表明,与最低健康生活方式评分(评分:0)相比,具有最高健康生活方式评分(评分:4)的参与者患高血压的比值比(OR)显著降低(0.21;95%CI:0.10,0.43;P-trend<0.001))。在调整模型中,与最低健康生活方式评分相比,最高健康生活方式评分的 OR 为:0.17;(95%CI:0.07,0.42;P-trend<0.001)用于血脂异常。

结论

高血压和血脂异常与健康生活方式评分呈负相关。需要采取健康的生活方式干预措施来降低高血压、血脂异常和促进人群健康。

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