使用 ArcScan Insight 100 对中国近视青年的睫状肌进行活体分析。

In vivo analysis of ciliary muscle in myopic Chinese young adults using ArcScan Insight 100.

机构信息

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.

Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan, China.

出版信息

Ophthalmic Physiol Opt. 2022 May;42(3):559-570. doi: 10.1111/opo.12965. Epub 2022 Mar 8.

DOI:10.1111/opo.12965

PMID:35261043

Abstract

OBJECTIVE

To analyse the morphological characteristics of the ciliary muscle (CM) and to explore its relationship with different ocular biometric parameters in myopic young Chinese adults.

METHODS

This observational, cross-sectional study included 50 right eyes from 50 myopic adults. The CM area (CMA), CM thickness (CMT) and CM length (CML) were measured using the ArcScan Insight 100. CMT was determined at three points: 1.0 mm (CMT-1), 2.0 mm (CMT-2) and 3.0 mm (CMT-3) posterior to the scleral spur. CML was measured on the scleral (CMLs) and vitreous (CMLv) aspects. The spherical equivalent refraction (SER), axial length (AL) and subfoveal choroidal thickness (SFCT) were examined to determine their associations with CM parameters (CMA, CML and CMT).

RESULTS

The mean SER and AL were -4.39 ± 2.29 D and 25.61 ± 1.15 mm, respectively. Compared with the nasal CMA, CML and CMT (CMT-1, CMT-2 and CMT-3) findings, the temporal CM parameters (CMA, CMLs, CMLv, CMT-1, CMT-2 and CMT-3) were found to be significantly thicker (all p < 0.001, except CMLv and CMT-1; p < 0.01). The nasal CMA was associated with the average corneal curvature (r = 0.30, p = 0.03) and SER (r = -0.30, p = 0.04). Nasal and temporal CMT-2 were negatively correlated with SER (r = -0.33 and -0.32, respectively, both p < 0.05). There was no correlation between CM parameters (except nasal CMLs, r = 0.31, p = 0.03) and SFCT, or between CM parameters and either the AL or anterior chamber depth (all p > 0.05).

CONCLUSION

These results suggest that there is temporal versus nasal asymmetry of the CM. CMA, CMT or CML did not vary with axial growth of the eye. The CM is not simply stretched as the eye elongates in myopic young adults.

摘要

目的

分析睫状肌的形态特征，并探讨其与近视中国年轻人不同眼部生物测量参数的关系。

方法

本研究为观察性、横断面研究，纳入了 50 名近视成年人的 50 只右眼。使用 ArcScan Insight 100 测量睫状肌面积（CMA）、睫状肌厚度（CMT）和睫状肌长度（CML）。在巩膜突后 1.0mm（CMT-1）、2.0mm（CMT-2）和 3.0mm（CMT-3）处测量 CMT。CML 在巩膜（CMLs）和玻璃体（CMLv）方面进行测量。检查等效球镜（SER）、眼轴（AL）和中心凹下脉络膜厚度（SFCT），以确定它们与 CM 参数（CMA、CML 和 CMT）的关系。

结果

平均 SER 和 AL 分别为-4.39±2.29 D 和 25.61±1.15mm。与鼻侧 CMA、CML 和 CMT（CMT-1、CMT-2 和 CMT-3）发现相比，颞侧 CM 参数（CMA、CMLs、CMLv、CMT-1、CMT-2 和 CMT-3）明显更厚（均 p<0.001，除了 CMLv 和 CMT-1；p<0.01）。鼻侧 CMA 与平均角膜曲率（r=0.30，p=0.03）和 SER（r=-0.30，p=0.04）相关。鼻侧和颞侧 CMT-2 与 SER 呈负相关（r=-0.33 和-0.32，均 p<0.05）。CM 参数（除了鼻侧 CMLs，r=0.31，p=0.03）与 SFCT 之间无相关性，或与 AL 或前房深度之间无相关性（均 p>0.05）。