Muramatsu Koichi, Kawada Noriyasu, Naganuma Hirokuni, Ishiwari Keiichi, Amagaya Suguru
The Jikei University Kashiwa Hospital, Department of Cardiac Surgery, Kashiwa-city, Chiba, Japan.
J Cardiol Cases. 2021 Aug 26;25(3):119-122. doi: 10.1016/j.jccase.2021.07.014. eCollection 2022 Mar.
Nonbacterial thrombotic endocarditis (NBTE) is relatively rare, with an identification rate of 1.6% at autopsy, and is associated with malignancy and systemic lupus erythematosus. Further, bioprosthetic valve NBTE is extremely rare, with only a few reports in the literature. To ensure appropriate treatment, it is essential to differentiate between NBTE from infective endocarditis (IE) as soon as possible, but this is difficult without information regarding underlying disease and sufficient time for careful investigation. Here, we report a case of recurrent NBTE of a bioprosthetic valve the day following surgery based on an initial diagnosis of IE. < Nonbacterial thrombotic endocarditis (NBTE) is a relatively rare condition associated with some malignancies and systemic lupus erythematosus. Without information on underlying disease and sufficient time for detailed investigation, it is difficult to distinguish NBTE from infective endocarditis (IE). Unlike IE, the treatment strategy of NBTE involves initiating systemic heparinization as soon possible. This study suggests that NBTE should be considered in cases of recurrent cerebral embolism, even without information indicating underlying pathology.>.
非细菌性血栓性心内膜炎（NBTE）相对罕见，尸检时的检出率为1.6%，且与恶性肿瘤和系统性红斑狼疮有关。此外，生物人工瓣膜NBTE极为罕见，文献中仅有少数报道。为确保进行恰当治疗，尽早将NBTE与感染性心内膜炎（IE）区分开来至关重要，但如果没有关于基础疾病的信息以及足够的时间进行仔细检查，这很难做到。在此，我们报告一例基于IE的初步诊断在术后次日发生生物人工瓣膜复发性NBTE的病例。<非细菌性血栓性心内膜炎（NBTE）是一种与某些恶性肿瘤和系统性红斑狼疮相关的相对罕见的病症。如果没有关于基础疾病的信息以及足够的时间进行详细检查，很难将NBTE与感染性心内膜炎（IE）区分开来。与IE不同，NBTE的治疗策略包括尽快开始全身性肝素化。本研究表明，即使没有表明基础病理的信息，在复发性脑栓塞病例中也应考虑NBTE。>
