Hamana Tomoyo, Yamamoto Hiroyuki, Takahashi Nobuyuki, Tsunamoto Hiroshi, Onishi Testuari, Sawada Takahiro, Nomura Yoshikatsu, Kawai Hiroya, Takaya Tomofumi
Division of Cardiovascular Medicine, Hyogo Brain and Heart Center, Himeji, Japan.
Division of Cardiovascular Surgery, Hyogo Brain and Heart Center, Himeji, Japan.
J Cardiol Cases. 2021 Sep 23;25(3):188-192. doi: 10.1016/j.jccase.2021.09.005. eCollection 2022 Mar.
Acute decompensated heart failure (ADHF) due to severe aortic stenosis (AS) and concomitant left ventricular outflow tract (LVOT) obstruction is a serious condition. Treatment with medication alone is sometimes difficult, and the efficacy of further interventional strategies has not been fully elucidated. In patients with high surgical risks, combination therapy using transcatheter aortic valve replacement (TAVR) and percutaneous alcohol septal ablation (ASA) is used as a non-surgical intervention. However, this treatment cannot be performed under unstable hemodynamic conditions. This report highlights the utility and efficacy of emergent balloon aortic valvuloplasty (BAV) in controlling heart failure and its potential to serve as a bridge to curative therapy, even in older patients with ADHF due to severe AS with concomitant LVOT obstruction. Furthermore, combination therapy with TAVR and percutaneous ASA could be safely performed after controlling for ADHF using BAV. Non-surgical management is a more feasible treatment option in older patients with ADHF who are at higher risk of complications during surgical intervention. < Management of acute decompensated heart failure (ADHF) due to severe aortic stenosis (AS) and concomitant left ventricular outflow tract (LVOT) obstruction can be difficult. Despite concomitant LVOT obstruction, emergent balloon aortic valvuloplasty is potentially useful and effective for controlling heart failure and could become a bridge to subsequent combination therapy using transcatheter aortic valve replacement and percutaneous alcohol septal ablation. This sequential non-surgical management is a novel strategy for older patients with high surgical risk and ADHF due to severe AS with concomitant LVOT obstruction.>.
由严重主动脉瓣狭窄(AS)及伴发的左心室流出道(LVOT)梗阻所致的急性失代偿性心力衰竭(ADHF)是一种严重病症。仅用药物治疗有时会很困难,而且进一步介入策略的疗效尚未完全阐明。对于手术风险高的患者,经导管主动脉瓣置换术(TAVR)和经皮酒精室间隔消融术(ASA)联合治疗被用作一种非手术干预措施。然而,这种治疗不能在血流动力学不稳定的情况下进行。本报告强调了急诊球囊主动脉瓣成形术(BAV)在控制心力衰竭方面的实用性和有效性,以及其作为根治性治疗桥梁的潜力,即使对于因严重AS伴LVOT梗阻而患有ADHF的老年患者也是如此。此外,在使用BAV控制ADHF后,可以安全地进行TAVR和经皮ASA联合治疗。对于在手术干预期间并发症风险较高的老年ADHF患者,非手术管理是一种更可行的治疗选择。< 因严重主动脉瓣狭窄(AS)及伴发的左心室流出道(LVOT)梗阻所致的急性失代偿性心力衰竭(ADHF)的管理可能具有挑战性。尽管存在伴发的LVOT梗阻,但急诊球囊主动脉瓣成形术对于控制心力衰竭可能是有用且有效的,并且可以成为后续使用经导管主动脉瓣置换术和经皮酒精室间隔消融术联合治疗的桥梁。这种序贯非手术管理是针对因严重AS伴LVOT梗阻而手术风险高的老年ADHF患者的一种新策略。>