Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Department of Clinical Laboratory, Department of Infection Prevention, Kyoto University Hospital, Kyoto, Japan.
Influenza Other Respir Viruses. 2022 Jul;16(4):690-695. doi: 10.1111/irv.12981. Epub 2022 Mar 9.
During the third wave of the COVID-19 pandemic at the end of 2020, clusters occurred frequently in aged-care facilities (ACFs), which put pressure on the medical field in Japan. Based on this experience, Kyoto University and Kyoto City collaborated to promote a citywide COVID-19 prevention strategy to prevent the spread of COVID-19 within ACFs. The aim of this study was to clarify the effect of the prevention strategy among ACFs in Kyoto City during the third and fifth waves of the pandemic.
During the study period, the following measures were adopted as the prevention strategy in all ACFs: (1) active polymerase chain reaction (PCR) mass testing and facility-wide testing when a single case was identified, (2) implementation of strategies to prevent transmission within a facility, and (3) vaccination program for ACFs.
Of the 1,144 facilities subjected to the mass testing, 71.0% participated in the whole program including active PCR testing. The remainder participated in the rest of the programs. The prevalence of ACF-related COVID-19 cases among total COVID-19 cases in Kyoto City decreased from 7.9% in the third wave to 4.1% in the fourth wave and 2.1% in the fifth wave. The incidence of clusters and proportion of severe elderly cases also decreased during the study period.
A city-wide multidisciplinary effort including PCR mass testing and a vaccination program in cooperation with a university and local administrative office successfully reduced the clusters and transmission in ACFs in Kyoto City, Japan.
在 2020 年底 COVID-19 疫情的第三波中,养老院(ACF)经常出现聚集性病例,这给日本的医疗领域带来了压力。基于这一经验,京都大学和京都市合作,共同推行全市范围的 COVID-19 预防策略,以防止 ACF 内 COVID-19 的传播。本研究旨在明确该策略在京都市第三波和第五波疫情期间对 ACF 的效果。
在研究期间,所有 ACF 均采取以下措施作为预防策略:(1)在发现单一病例时,主动进行大规模聚合酶链反应(PCR)检测和全机构检测;(2)实施防止机构内传播的策略;(3)为 ACF 接种疫苗。
在接受大规模检测的 1144 个设施中,71.0% 参与了包括主动 PCR 检测在内的整个计划。其余的参与了其他项目。在京都市,ACF 相关 COVID-19 病例在 COVID-19 总病例中的比例从第三波的 7.9%下降到第四波的 4.1%和第五波的 2.1%。聚集性病例的发生率和重症老年病例的比例也在研究期间下降。
包括大规模 PCR 检测和与大学及地方行政部门合作的疫苗接种计划在内的全市多学科努力,成功减少了日本京都市 ACF 中的聚集性病例和传播。