Department of Infectious Diseases, Wenzhou Center Hospital, Wenzhou, 325000, Zhejiang Province, China.
Department of Pathology, Wenzhou Center Hospital, Wenzhou, 325000, Zhejiang Province, China.
BMC Infect Dis. 2022 Mar 9;22(1):238. doi: 10.1186/s12879-022-07230-8.
Gastrointestinal involvement is not uncommon in patients with disseminated talaromycosis, but successful management of massive gastrointestinal bleeding and hemorrhagic shock secondary to talaromycosis is rarely reported. Clinical management strategies for these patients have not been well documented.
Here, we reported a case of disseminated talaromycosis with recurrent gastrointestinal bleeding and hemorrhagic shock who was successfully alleviated solely with medical treatment.
Early diagnosis and treatment for Talaromyces marneffei, intravenous fluid resuscitation, hemostatic therapy and blood transfusion are all essential for talaromycosis complicated with gastrointestinal bleeding and hemorrhagic shock. It is also necessary to warn about the possibility of bleeding induced or aggravated by endoscopic biopsy trauma.
播散性马尔尼菲篮状菌病患者常伴有胃肠道受累,但播散性马尔尼菲篮状菌病所致的大量胃肠道出血和出血性休克的成功治疗鲜有报道。这些患者的临床管理策略尚未得到很好的记录。
在此,我们报告了一例播散性马尔尼菲篮状菌病伴反复胃肠道出血和出血性休克的病例,该患者仅通过药物治疗即成功缓解。
早期诊断和治疗马尔尼菲篮状菌、静脉补液复苏、止血治疗和输血对于并发胃肠道出血和出血性休克的马尔尼菲篮状菌病均至关重要。还需要警惕内镜活检创伤引起或加重出血的可能性。