Sawarkar Prashant, Mehra Bhupendra, Dubhashi Siddharth Pramod, Kamal Fatema
Department of Surgery, All India Institute of Medical Sciences, Nagpur, Maharashtra State, India.
Department of Pathology, All India Institute of Medical Sciences, Nagpur, Maharashtra State, India.
Int J Appl Basic Med Res. 2022 Jan-Mar;12(1):51-53. doi: 10.4103/ijabmr.ijabmr_365_21. Epub 2022 Jan 31.
Hibernoma is a rare benign tumor of brown fat origin. It presents as a painless, slowly growing soft tissue tumor mimicking lipoma or liposarcoma, usually affecting adults, with a slight male predominance and a peak of incidence between the third and fourth decades of life. This is a case report of 35-year male, who presented with a mobile, fluctuant and transilluminant, swelling of 7 cm × 5 cm, on medial aspect of the right upper leg. Ultrasonography showed well-defined cystic lesion of varied echotexture with dense internal echoes and septation. Lesion was excised in-toto. On gross examination, it was a subcutaneous, multiseptate cyst containing clear serous fluid with cholesterol crystals with a solid area of 3 cm × 2 cm. Histopathological examination revealed large tumor cells with abundant granular (multivacuolated) cytoplasm. Postoperative recovery period was uneventful. We present this case as cystic degeneration in case of hibernoma.
冬眠瘤是一种罕见的起源于棕色脂肪的良性肿瘤。它表现为无痛、生长缓慢的软组织肿瘤,类似脂肪瘤或脂肪肉瘤,通常累及成年人,男性略占优势,发病高峰在30至40岁之间。这是一例35岁男性病例,其右大腿内侧出现一个可活动、有波动感且透光的7厘米×5厘米肿物。超声检查显示为边界清晰的囊性病变,回声质地多样,内部有密集回声和分隔。病变被完整切除。大体检查显示为一个皮下多房囊肿,内含清亮浆液及胆固醇结晶,并有一个3厘米×2厘米的实性区域。组织病理学检查发现大的肿瘤细胞,其细胞质丰富且呈颗粒状(多泡状)。术后恢复期顺利。我们将此病例呈现为冬眠瘤的囊性变。