Ellis W A, O'Brien J J, Neill S D, Bryson D G
Vet Microbiol. 1986 Mar;11(3):293-9. doi: 10.1016/0378-1135(86)90031-3.
Almost the full range of clinical signs observed in pregnant cattle naturally infected with Leptospira interrogans serovar hardjo was observed in this experimental study in which 22 heifers were infected by intraplacentome inoculation with serovar hardjo strains. These features included abortion, mummification, stillbirth, premature and term birth of weak calves and full-term birth of live apparently healthy calves. Leptospires were demonstrated in all but three calves by culture and or immunofluorescence.
在这项实验研究中，通过胎盘内接种问号钩端螺旋体哈氏血清型菌株感染了22头小母牛，观察到的临床症状几乎涵盖了自然感染该血清型的怀孕母牛所出现的所有症状。这些症状包括流产、木乃伊化、死产、弱犊早产和足月产以及健康活犊足月产。除三头犊牛外，通过培养和（或）免疫荧光法在所有犊牛中都检测到了钩端螺旋体。
