Mali B, Joshi J V, Wagle U, Hazari K, Shah R, Chadha U, Gokral J, Bhave G
Acta Cytol. 1986 Jul-Aug;30(4):367-71.
Cervical smears from 1,784 women who attended the family planning clinics of the Institute for Research in Reproduction were examined for the presence of Actinomyces-like organisms. Among 815 intrauterine contraceptive device (IUD) users, the repeat smears from 57 women were positive for Actinomyces-like organisms, giving a prevalence rate of 6.99%. Immunofluorescent staining using specific antisera confirmed the presence of A. israelii in all 57 women. Forty IUD users whose smears were positive for Actinomyces-like organisms underwent bacteriologic culture studies; A. israelii was isolated in 23 of these cases. The clinical findings at the time of smear collection in the 57 IUD users were within normal limits. The initial cervical smears of all IUD users and both the initial and repeat smears of all nonusers were negative for Actinomyces-like organisms. The data indicate that prolonged use (greater than 2 years) of an inert or copper intrauterine device promotes the overgrowth of Actinomyces in the vagina and that this can be detected by routine cervical cytology.
对1784名前往生殖研究所计划生育门诊就诊的女性的宫颈涂片进行检查，以确定是否存在放线菌样微生物。在815名宫内节育器（IUD）使用者中，57名女性的重复涂片放线菌样微生物呈阳性，患病率为6.99%。使用特异性抗血清进行免疫荧光染色证实，所有57名女性均存在以色列放线菌。40名涂片放线菌样微生物呈阳性的IUD使用者接受了细菌培养研究；其中23例分离出以色列放线菌。57名IUD使用者涂片采集时的临床检查结果均在正常范围内。所有IUD使用者的初次宫颈涂片以及所有非使用者的初次和重复涂片放线菌样微生物均为阴性。数据表明，惰性或含铜宫内节育器的长期使用（超过2年）会促使阴道内放线菌过度生长，这可通过常规宫颈细胞学检查检测到。
