Freund Anne, Desch Steffen, Pöss Janine, Sulimov Dmitry, Sandri Marcus, Majunke Nicolas, Thiele Holger
Department of Internal Medicine/Cardiology, Heart Center Leipzig, University of Leipzig, Strümpellstr. 39, 04289 Leipzig, Germany.
Leipzig Heart Institute, 04289 Leipzig, Germany.
J Clin Med. 2022 Feb 25;11(5):1256. doi: 10.3390/jcm11051256.
Mortality in infarct-related cardiogenic shock (CS) remains high, reaching 40-50%. In refractory CS, active mechanical circulatory support devices including veno-arterial extracorporeal membrane oxygenation (VA-ECMO) are rapidly evolving. However, supporting evidence of VA-ECMO therapy in infarct-related CS is low. The current review aims to give an overview on the basics of VA-ECMO therapy, current evidence, ongoing trials, patient selection and potential complications.
梗死相关的心源性休克(CS)死亡率仍然很高,达到40%-50%。在难治性CS中,包括静脉-动脉体外膜肺氧合(VA-ECMO)在内的主动机械循环支持装置正在迅速发展。然而,VA-ECMO治疗在梗死相关CS中的支持证据不足。本综述旨在概述VA-ECMO治疗的基础、现有证据、正在进行的试验、患者选择和潜在并发症。