Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Pampa, Uruguaiana, Uruguaiana 97501-970, RS, Brazil.
Laboratório de Síntese Orgânica Limpa-LaSOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, Pelotas 96010-900, RS, Brazil.
Molecules. 2022 Feb 28;27(5):1597. doi: 10.3390/molecules27051597.
Organoselenium compounds have been successfully applied in biological, medicinal and material sciences, as well as a powerful tool for modern organic synthesis, attracting the attention of the scientific community. This great success is mainly due to the breaking of paradigm demonstrated by innumerous works, that the selenium compounds were toxic and would have a potential impact on the environment. In this update review, we highlight the relevance of these compounds in several fields of research as well as the possibility to synthesize them through more environmentally sustainable methodologies, involving catalytic processes, flow chemistry, electrosynthesis, as well as by the use of alternative energy sources, including mechanochemical, photochemistry, sonochemical and microwave irradiation.
有机硒化合物已成功应用于生物、医学和材料科学领域，并且是现代有机合成的有力工具，引起了科学界的关注。这一巨大成功主要归因于无数研究工作所证明的突破，即硒化合物具有毒性，会对环境产生潜在影响。在本次更新的综述中，我们强调了这些化合物在几个研究领域的相关性，以及通过更具环境可持续性的方法来合成它们的可能性，包括催化过程、流动化学、电化学以及使用替代能源，包括机械化学、光化学、声化学和微波辐射。
