Department of Electrical and Computer Engineering, McGill University, Montreal, QC H3A 0E9, Canada.
Sensors (Basel). 2022 Mar 2;22(5):1955. doi: 10.3390/s22051955.
Considerable exploration has been done in recent years to exploit the reported inherent dielectric contrast between healthy and malignant tissues for a range of medical applications. In particular, microwave technologies have been investigated towards new diagnostic medical tools. To assess the performance and detection capabilities of such systems, tissue-mimicking phantoms are designed for controlled laboratory experiments. We here report phantoms developed to dielectrically represent malign skin lesions such as liposarcoma and nonsyndromic multiple basal cell carcinoma. Further, in order to provide a range of anatomically realistic scenarios, and provide meaningful comparison between different phantoms, cancer-mimicking lesions are inserted into two different types of skin phantoms with varying tumor-skin geometries. These configurations were measured with a microwave dielectric probe (0.5-26.5 GHz), yielding insight into factors that could affect the performance of diagnostic and detection tools.
近年来，人们对利用健康组织和恶性组织之间报道的固有介电对比度进行了大量探索，以期将其应用于一系列医学领域。特别是，微波技术已经被用于开发新的诊断医疗工具。为了评估这些系统的性能和检测能力，人们设计了组织模拟体模，以便在受控的实验室环境中进行实验。本文报告了为模拟脂肪肉瘤和非综合征性多发性基底细胞癌等恶性皮肤病变而开发的体模。此外，为了提供一系列具有解剖学现实意义的场景，并在不同的体模之间进行有意义的比较，我们将癌症模拟病变插入到两种不同类型的皮肤体模中，这些体模具有不同的肿瘤-皮肤几何形状。使用微波介电探头（0.5-26.5GHz）对这些配置进行了测量，深入了解了可能影响诊断和检测工具性能的因素。
